首页> 外文期刊>Folia neuropathologica >Cerebral amyloid angiopathy as a cause of an extensive brain hemorrhage in adult patient with Down's syndrome - a case report.
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Cerebral amyloid angiopathy as a cause of an extensive brain hemorrhage in adult patient with Down's syndrome - a case report.

机译:脑淀粉样血管病是成年唐氏综合症患者广泛脑出血的原因-病例报告。

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摘要

A case of 54-year old woman who deceased due to consequence of extensive brain hemorrhage is presented. The patient was admitted to our Department of Neurology due to progressive quadriparesis as a complication of the cervical spinal cord compressive myelopathy. On the third day after neurosurgical decompression of the spinal cord sudden worsening of neurological and general condition was observed, finally caused death. An autopsy study revealed an extensive brain lobar hemorrhage and a dorsal-ventral compression of the cervical spinal cord. Alzheimer's disease-type degenerative changes with concomitant CAA were seen in light microscope examination. Extensive foci of demyelination were found especially in dorsal funiculi of the cervical spinal cord. Smaller foci of demyelination were present in anterior funiculi due to the stenosis of vertebral canal.
机译:介绍了一名因广泛脑出血而死亡的54岁女性病例。该患者因进行性四肢瘫痪作为颈脊髓压迫性脊髓病的并发症而进入我们的神经内科。脊髓神经外科减压后的第三天,观察到神经和全身状况突然恶化,最终导致死亡。尸检研究显示广泛的脑叶出血和颈脊髓背腹压迫。在光学显微镜检查中可以观察到阿尔茨海默氏病类型的变性变化以及伴随的CAA。广泛的脱髓鞘病灶被发现,尤其是在颈脊髓的背部真菌中。由于椎管狭窄,较小的脱髓鞘病灶出现在前部真菌。

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