...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Canadian Journal of Physiology and Pharmacology >L-cysteine supplementation as an adjuvant therapy for type-2 diabetes
【24h】

L-cysteine supplementation as an adjuvant therapy for type-2 diabetes

机译：补充L-半胱氨酸作为2型糖尿病的辅助治疗

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Diabetes remains a major public health issue. According to the American Diabetes Association, 23.5 million, or 10.7% of people in the USA aged 20 years and older, have diabetes. Type-2 diabetes is treated both by controlling the diet and with oral hypoglycemic drugs. However, for many patients, achieving a tight control of glucose is difficult with current regimens. This chapter discusses a relatively low-cost dietary supplement that could be used as an adjuvant therapy for type-2 diabetes. A review of the literature indicates that cysteine-rich whey protein improves glucose metabolism in diabetic animals and type-2 diabetic patients. Similarly, in animal studies, improvement in glucose metabolism is observed after supplementation with L-cysteine, or molecules containing a cysteine moiety. This chapter discusses the biochemical mechanisms by which L-cysteine can upregulate the insulin-dependent signaling cascades of glucose metabolism. Further studies are needed to examine whether clinical interventions using L-cysteine as an adjuvant therapy indeed help to control glycemia and vascular inflammation in the diabetic patient population.
机译：糖尿病仍然是主要的公共卫生问题。根据美国糖尿病协会的数据，有2350万糖尿病患者，即美国20岁及以上年龄人群的10.7％。通过控制饮食和口服降糖药可以治疗2型糖尿病。然而，对于许多患者而言，采用当前方案很难实现对葡萄糖的严格控制。本章讨论可以用作2型糖尿病辅助治疗的相对低成本的膳食补充剂。文献综述表明，富含半胱氨酸的乳清蛋白可改善糖尿病动物和2型糖尿病患者的葡萄糖代谢。同样，在动物研究中，补充L-半胱氨酸或含有半胱氨酸部分的分子后，葡萄糖代谢得到改善。本章讨论了L-半胱氨酸可以上调葡萄糖代谢的胰岛素依赖性信号传导级联反应的生化机制。需要进一步的研究来检查使用L-半胱氨酸作为辅助疗法的临床干预措施是否确实有助于控制糖尿病患者群体的血糖和血管炎症。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号