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首页> 外文期刊>Frontiers in neuroendocrinology >A meta-analytic review of the correlation between peripheral oxytocin and cortisol concentrations
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A meta-analytic review of the correlation between peripheral oxytocin and cortisol concentrations

机译：外周催产素与皮质醇浓度之间相关性的荟萃分析

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The stress dampening effects of exogenous oxytocin in humans have been well documented. However, the relation between endogenous oxytocin and cortisol is poorly understood. We conducted a meta analysis on the correlation between oxytocin and cortisol levels measured at baseline (k = 24, N = 739). The effect size for the baseline correlation statistic was small (Pearson r = 0.163, p = 0.008), with high heterogeneity (I-2 = 67.88%). Moderation analysis revealed that studies where participants anticipated an experimental manipulation evidenced a greater positive correlation compared to those that did not (Pearson r = 0.318, p = 0.006). A supplementary analysis including additional studies indicated that oxytocin levels in unextracted samples were 60 times higher when using this questionable practice. The findings suggest that the interplay between oxytocin and cortisol is dynamic and sensitive to the anticipation of stress or novelty. Furthermore, extraction of oxytocin appears to be an essential methodological practice. (C) 2016 Elsevier Inc. All rights reserved.
机译：外源性催产素对人体的压力抑制作用已得到充分证明。但是，内源性催产素和皮质醇之间的关系知之甚少。我们对在基线测量的催产素和皮质醇水平之间的相关性进行了荟萃分析（k = 24，N = 739）。基线相关统计量的影响量较小（Pearson r = 0.163，p = 0.008），异质性较高（I-2 = 67.88％）。适度分析显示，与未参加实验的参与者相比，参与者进行实验预期的研究显示出更大的正相关性（Pearson r = 0.318，p = 0.006）。包括其他研究在内的补充分析表明，使用这种可疑做法时，未提取样品中的催产素水平高60倍。这些发现表明催产素和皮质醇之间的相互作用是动态的，并且对预期的压力或新颖性敏感。此外，催产素的提取似乎是必不可少的方法学实践。 （C）2016 Elsevier Inc.保留所有权利。

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