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首页> 外文期刊>Canadian Veterinary Journal: La Revue Veterinaire Canadienne. >Microbiological and histopathological findings in cases of fatal bovine respiratory disease of feedlot cattle in Western Canada.
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Microbiological and histopathological findings in cases of fatal bovine respiratory disease of feedlot cattle in Western Canada.

机译：加拿大西部饲养场牛的致命牛呼吸道疾病病例的微生物学和组织病理学发现。

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摘要

The aim of this study was to describe the microbiologic agents and pathologic processes in fatal bovine respiratory disease (BRD) of feedlot cattle and to investigate associations between agents and pathologic processes. Ninety feedlot calves diagnosed at necropsy with BRD and 9 control calves without BRD were examined, using immunohistochemical (IHC) staining and histopathologic studies. Mannheimia haemolytica (MH) (peracute, acute, and subacute cases) and Mycoplasma bovis (MB) (subacute, bronchiolar, and chronic cases) were the most common agents identified in fatal BRD cases. Significant associations (P < 0.10) were detected between microbiologic agents and between agents and pathologic processes. When IHC staining was used, 25/26 (96%) of animals that were positive for bovine viral diarrhea virus (BVDV) were also positive for MH; 12/15 (80 %) of animals that were positive for Histophilus somni (HS) were also positive for MB; and all of the animals that were positive for HS were negative for MH and BVDV. This quantitative pathological study demonstrates that several etiologic agents and pathologic processes are involved in fatal BRD of feedlot cattle.
机译：这项研究的目的是描述饲养场牛致命性牛呼吸道疾病（BRD）中的微生物学因素和病理过程，并研究这些因素与病理过程之间的关联。使用免疫组织化学（IHC）染色和组织病理学检查检查了90例在尸检中诊断为BRD的肥育小牛和9例没有BRD的对照牛。在致命的BRD病例中，最常见的病原体是溶血性曼海姆氏菌（MH）（急性，急性和亚急性病例）和牛支原体（MB）（亚急性，细支气管和慢性病例）。在微生物制剂之间以及制剂与病理过程之间检测到显着关联（P <0.10）。使用IHC染色时，牛病毒性腹泻病毒（BVDV）阳性的动物中有25/26（96％）的MH也呈阳性。索马氏嗜血杆菌（HS）阳性的动物中有12/15（80％）的MB也呈阳性。而所有HS阳性的动物的MH和BVDV均为阴性。这项定量病理研究表明，肥育场牛致命性BRD涉及多种病原体和病理过程。

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