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首页> 外文期刊>Fungal Biology Reviews >Detection and response of the Neurospora crassa circadian clock to light and temperature
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Detection and response of the Neurospora crassa circadian clock to light and temperature

机译：神经孢霉生物钟对光和温度的检测和响应

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摘要

Circadian clocks are molecular timekeepers that provide organisms with a means to predict and prepare for environmental change. The filamentous fungus Neurospora crassa has provided an excellent model system in which the underlying molecular basis of circadian clocks has been elucidated. In Neurospora, and in other eukaryotes, circadian rhythmicity emerges from a network of positive and negative feedback regulation acting on clock genes and proteins. An essential attribute of the clock is that it can detect and respond to the daily cycle of light and dark and temperature change and integrate these environmental time cues to give an accurate depiction of the external day. In Neurospora many of the molecules that sense the daily changes in light and temperature are known. In this review we describe Neurospora's clock mechanism and how it is tuned to the real world by light and temperature
机译：昼夜生物钟是分子计时器，可为生物体提供预测和为环境变化做准备的手段。丝状真菌Neurospora crassa提供了一个出色的模型系统，其中阐明了生物钟的潜在分子基础。在Neurospora和其他真核生物中，昼夜节律性来自作用于时钟基因和蛋白质的正反馈和负反馈调节网络。时钟的一个基本属性是，它可以检测和响应明暗变化和温度变化的每日周期，并整合这些环境时间提示，以准确地描述外部一天。在Neurospora中，许多感知光和温度每日变化的分子都是已知的。在这篇评论中，我们描述了Neurospora的时钟机制，以及如何通过光和温度将其调整到现实世界

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