首页> 外文期刊>Canadian journal of anesthesia: Journal canadien d'anesthesie >Ophthalmic artery blood flow velocity increases during hypocapnia: (La vitesse circulatoire de l'artere ophtalmique augmente pendant l'hypocapnie).
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Ophthalmic artery blood flow velocity increases during hypocapnia: (La vitesse circulatoire de l'artere ophtalmique augmente pendant l'hypocapnie).

机译:低碳酸血症期间眼动脉血流速度增加:(低碳酸血症期间眼动脉循环血流速度增加)。

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PURPOSE: The effects of anesthetic management on blood flow to the optic nerve have not been well-studied. The ophthalmic artery provides the majority of the blood supply to the optic nerve via several smaller branches. Retinal blood flow has been shown to react to carbon dioxide (CO(2)) similar to intracranial vessels, but insufficient data exist for the ophthalmic artery. The purpose of this study is to examine the CO(2)-reactivity of the ophthalmic artery. METHODS: Eight healthy awake subjects aged 28 to 50 yr were tested for CO(2)-reactivity in the ophthalmic artery using transcranial Doppler (TCD) insonation of blood flow velocity (V(op)), while simultaneously recording the V(op) of the middle cerebral artery (V(mca)) as an internal control. V(op) and V(mca) recordings were made under hypocapnic, normocapnic and hypercapnic conditions. RESULTS: The CO(2)-reactivity slope of V(mca) was 3.27% per mmHg PaCO(2). From normocapnia to hypercapnia, V(op) did not change significantly (mean +/- SD, 18 +/- 4cm*sec(-1) to 18 +/- 6 cm*sec(-1)), (end-tidal CO(2), etCO(2), = 43 +/- 5 mmHg to 53 +/- 4 mmHg, respectively). In contrast, V(op) increased significantly under hypocapnic conditions (etCO(2) = 26 +/- 4 mmHg) to 25 +/- 5 cm*sec(-1) (P < 0.05). The CO(2)-reactivity slope of V(op) from normocapnia to hypocapnia was 2.57% per mmHg. CONCLUSIONS: This study demonstrates that V(op) increases with hypocapnia, but is unaffected by hypercapnia. The anastomoses of the ophthalmic artery with the external carotid artery, which displays a relatively fixed resistance, may account for these findings.
机译:目的:麻醉管理对视神经血流的影响尚未得到很好的研究。眼动脉通过几个较小的分支向视神经提供大部分血液供应。视网膜血流已显示出对类似于颅内血管的二氧化碳(CO(2))的反应,但眼科动脉的数据不足。这项研究的目的是检查眼科动脉的CO(2)反应性。方法:使用经颅多普勒(TCD)超声测血流速度(V(op)),同时记录V(op),对8名年龄在28至50岁的健康清醒受试者的眼动脉中CO(2)反应性进行了测试。大脑中动脉(V(mca))作为内部对照。 V(op)和V(mca)记录是在低碳酸血症,正常碳酸血症和高碳酸血症的情况下进行的。结果:V(mca)的CO(2)反应斜率为3.27%/ mmHg PaCO(2)。从正常碳酸血症到高碳酸血症,V(op)没有显着变化(平均+/- SD,18 +/- 4cm * sec(-1)到18 +/- 6 cm * sec(-1)),(潮气末CO(2),etCO(2)分别为43 +/- 5 mmHg至53 +/- 4 mmHg)。相反,在低碳酸血症条件下(etCO(2)= 26 +/- 4 mmHg),V(op)显着增加至25 +/- 5 cm * sec(-1)(P <0.05)。 V(op)从高碳酸血症到低碳酸血症的CO(2)反应性斜率为2.57%/ mmHg。结论:本研究证明低碳酸血症会增加V(op),但不受高碳酸血症的影响。眼动脉与颈外动脉的吻合显示相对固定的阻力,可能解释了这些发现。

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