• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Materials transactions >Formation and in Vivo Evaluation of Carbonate Apatite and Carbonate Apatite/CaCO_3 Composite Films Using the Thermal Substrate Method in Aqueous Solution
【24h】

Formation and in Vivo Evaluation of Carbonate Apatite and Carbonate Apatite/CaCO_3 Composite Films Using the Thermal Substrate Method in Aqueous Solution

机译：水溶液中热基质法形成碳酸盐磷灰石和碳酸盐磷灰石/ CaCO_3复合膜的研究及体内评价

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

We have studied the formation and carried out an in vivo evaluation of carbonate apatite (CO_3-Ap) and CO_3-Ap/CaCO_3 composite coatings on titanium substrates using the thermal substrate method. The coatings were formed on commercial pure titanium rods (diameter = 2 mm, length = 5 mm) and plates (thickness = 0.3 mm) by the thermal substrate method in an aqueous solution that contained Ca(H_2PO_4)_2, CaCl_2, and NaHCO_3. The coating experiments were conducted at 40-140 deg C and pH = 8 for periods of 15 or 30 min. The coating temperature and NaHCO_3 of the solution had a significant influence on the surface morphology (net-like, plate-like, needle-like, or sphere-like), the phase (single phase of CO_3-Ap or binary phase of CO_3-AP and CaCO_3), and the carbonate content in the precipitated films. A subsequent autoclave treatment also had an effect on the films. A coated rod was implanted in a 10 weeks old male rat's tibia with a non-coated titanium rod being used as a control. The constructs were retrieved after a period of 14 d postimplantation and examined for new bone formation and for tissue response in the cancellous and cortical bone parts, respectively. Single-phase sphere-like CO_3-Ap had high osteoconductivity in the cortical bone region, and this increased with increasing carbonate content in the films. However, the osteoconductivity of the CO_3-Ap/CaCO_3 composite coatings decreased with increasing total carbonate content.
机译：我们已经研究了形成过程，并使用热基底方法对钛基底上的碳酸盐磷灰石（CO_3-Ap）和CO_3-Ap / CaCO_3复合涂层进行了体内评估。通过热基质方法在包含Ca（H_2PO_4）_2，CaCl_2和NaHCO_3的水溶液中，通过热基质方法在市售的纯钛棒（直径= 2 mm，长度= 5 mm）和板（厚度= 0.3 mm）上形成涂层。涂层实验在40-140摄氏度，pH = 8的条件下进行15或30分钟。溶液的涂覆温度和NaHCO_3对表面形态（网状，板状，针状或球状），相（CO_3-Ap的单相或CO_3-的二元相）有显着影响。 AP和CaCO_3），以及沉淀膜中的碳酸盐含量。随后的高压灭菌处理也对薄膜有影响。将有涂层的棒植入10周大的雄性大鼠胫骨中，将未涂层的钛棒用作对照。植入后14天后取回构建体，并分别检查松质和皮质骨部分中的新骨形成和组织反应。单相球形CO_3-Ap在皮质骨区域具有较高的骨电导率，并且随着膜中碳酸盐含量的增加而增加。但是，CO_3-Ap / CaCO_3复合涂层的骨传导性随总碳酸盐含量的增加而降低。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号