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On the Mechanism of Erythrocyte Hemolysis Induced by Photooxidized Psoralen

机译:光氧化补骨脂素诱导红细胞溶血的机制

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摘要

Contemporary concepts on a possible mechanism of erythrocyte hemolysis induced by photooxidized psoralen - the medicinal photosensitizing furocoumarin - are reviewed. The hypothesis on the mechanochemical mechanism of hemolysis is considered in view of recent data on photoinduced aggregation in photooxidized psoralen solutions. Appropriate chemical structures of photoproduct hemolysins and aggregating photoproducts are discussed.
机译:综述了有关光氧化补骨脂素引起的红细胞溶血的可能机理的当代概念-药用光敏性呋喃香豆素-。考虑到关于光氧化补骨脂素溶液中光诱导聚集的最新数据,考虑了溶血的机械化学机理的假说。讨论了光产物溶血素和聚集的光产物的适当化学结构。

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