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Age-related changes in ultrastructure of mitochondria. Effect of SkQ1

机译:年龄相关的线粒体超微结构变化。 SkQ1的作用

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摘要

For many years, investigators have attempted to identify unique ultrastructural conditions of mitochondria related to aging. However, this did not result in definitive results. At present, this issue has again become of topical interest due to development of the mitochondrial theory of aging and of engineering of a novel antioxidant class known as mitochondria-targeted antioxidants. The review briefly discusses experimental results that, from our perspective, allow the most objective understanding regarding age-related changes in mitochondrial ultrastructure.
机译:多年来,研究人员一直试图确定与衰老有关的线粒体独特的超微结构条件。但是,这并未产生确定的结果。目前,由于衰老的线粒体理论的发展和新型抗氧化剂类(线粒体靶向抗氧化剂)的工程化发展,这个问题再次引起了人们的关注。这篇综述简要讨论了实验结果,从我们的角度出发,可以对线粒体超微结构的年龄相关变化提供最客观的了解。

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