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首页> 外文期刊>Medical image analysis >Spatiotemporal clustering of fMRI time series in the spectral domain.
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Spatiotemporal clustering of fMRI time series in the spectral domain.

机译:fMRI时间序列在频谱域中的时空聚类。

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摘要

We propose a new method for the analysis of functional magnetic resonance images (fMRI). The decision that a voxel v0 is activated is based not solely on the value of the fMRI signal at v0, but rather on the comparison of all time series s(v)(t) in a small neighborhood Nv0 around v0. Our approach explicitly takes into account the intrinsic spatiotemporal correlations that exist in the data. We focus on experimental designs with periodic stimuli, and therefore we can capture most of the features of the BOLD signal with a low dimensional subspace in the frequency domain. The presence of activated time series can be detected by partitioning the time series in this low dimensional space. Experiments with simulated data, and experimental fMRI data, demonstrate that our approach can outperform standard methods of analysis, such as the t-test.
机译:我们提出了一种新的方法来分析功能磁共振图像(fMRI)。激活体素v0的决定不仅基于v0处的fMRI信号的值,而且还基于v0附近小邻域Nv0中所有时间序列s(v)(t)的比较。我们的方法明确考虑了数据中存在的内在时空相关性。我们专注于具有周期性刺激的实验设计,因此我们可以在频域中捕获具有低维子空间的BOLD信号的大多数特征。可以通过在此低维空间中划分时间序列来检测激活的时间序列的存在。使用模拟数据和实验性fMRI数据进行的实验表明,我们的方法可以胜过标准的分析方法,例如t检验。

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