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首页> 外文期刊>Maturitas: International Journal for the Study of the Climacteric >PIXI bone density screening for osteoporosis in postmenopausal women.
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PIXI bone density screening for osteoporosis in postmenopausal women.

机译：绝经后妇女骨质疏松症的PIXI骨密度筛查。

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OBJECTIVES: The aim of this study was to evaluate a pragmatic screening programme for osteoporosis based on the identification of known risk factors. A secondary aim was to assess the validity of peripheral instantaneous X-ray imager (PIXI) scanning against dual energy X-ray absorptiometry (DEXA) in women identified as having osteopenia. METHODS: A cross-sectional two stage screening programme. The study was carried out in 14 practices in Surrey. Women aged 60-80 years of age were screened with a questionnaire. Those identified with one or more risk factors were offered a PIXI scan of the ankle in their own surgery. Those with an intermediate score on PIXI scan were offered a DEXA scan of hip, spine and forearm. RESULTS: Four thousand six hundred and forty-six women completed questionnaires, 2688 had a PIXI scan and 553 were found to be at high risk of osteoporosis. Multivariate analysis identified the three most important risk factors associated with increased risk of osteoporotic fracture as age, a previous fracture and the presence of a stooped posture. Hormone replacement therapy (HRT) was shown to be protective. Twenty three percent of women with an intermediate score on PIXI scan were found to have osteoporosis on DEXA scan of hip and spine. CONCLUSIONS: PIXI scanning proved acceptable, practicable but only had moderate comparability with DEXA. The findings suggest that patients over the age of 60 years with a history of a fracture or evidence of spinal collapse are likely to have osteoporosis and should be offered screening. HRT past the menopause would seem to confer benefit and the recent reduction in its use may lead to increasing numbers of women suffering osteoporotic fractures.
机译：目的：本研究的目的是在确定已知危险因素的基础上评估实用的骨质疏松筛查程序。第二个目的是评估在确定患有骨质疏松症的女性中，针对双能X线骨密度仪（DEXA）进行外围瞬时X射线成像仪（PIXI）扫描的有效性。方法：横断面两阶段筛查程序。该研究在萨里的14个实践中进行。用问卷调查年龄在60-80岁之间的女性。对那些被发现具有一个或多个危险因素的人，在他们自己的手术中对他们的脚踝进行了PIXI扫描。对那些在PIXI扫描中得分为中级的患者，进行了臀部，脊椎和前臂的DEXA扫描。结果：406例女性完成问卷，2688例进行了PIXI扫描，553例患骨质疏松症的高风险。多变量分析确定了与骨质疏松性骨折的风险增加相关的三个最重要的风险因素：年龄，先前的骨折和弯曲的姿势。激素替代疗法（HRT）具有保护作用。在PIXI扫描中得分为中等的女性中，有23％的髋部和脊柱DEXA扫描发现患有骨质疏松症。结论：PIXI扫描被证明是可接受的，可行的，但与DEXA的可比性中等。研究结果表明，有骨折史或脊柱塌陷迹象的60岁以上患者很可能患有骨质疏松症，应进行筛查。绝经后的HRT似乎可以带来益处，最近减少使用它可能导致患有骨质疏松性骨折的女性人数增加。

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