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In vivo heating of magnetic nanoparticles in alternating magnetic field.

机译:在交变磁场中体内加热磁性纳米粒子。

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摘要

We have evaluated heating capabilities of new magnetic nanoparticles. In in vitro experiments they were exposed to an alternating magnetic field with frequency 3.5 MHz and induction 1.5 mT produced in three turn pancake coil. In in vivo experiments rats with injected magnetic nanoparticles were also exposed to an ac field. An optimal increase of temperature of the tumor to 44 degrees C was achieved after 10 minutes of exposure. Obtained results showed that magnetic nanoparticles may be easily heated in vitro as well as in vivo, and may be therefore useful for hyperthermic therapy of cancer.
机译:我们已经评估了新型磁性纳米粒子的加热能力。在体外实验中,它们暴露于三匝煎饼线圈中产生的频率为3.5 MHz和感应强度为1.5 mT的交变磁场中。在体内实验中,注射了磁性纳米颗粒的大鼠也暴露于交流场。暴露10分钟后,肿瘤的温度最佳升高至44摄氏度。所获得的结果表明,磁性纳米颗粒可以在体外以及体内容易加热,因此可用于癌症的高温治疗。

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