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Do psychological interventions reduce depression in hemodialysis patients?: A meta-analysis of randomized controlled trials following PRISMA

机译：心理干预措施是否可以减少血液透析患者的抑郁情绪？：PRISMA之后的随机对照试验的荟萃分析

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Background:Depression is highly prevalent in hemodialysis patients and results in poor patient outcomes. Although psychological interventions are being developed and used for these patients, there is uncertainty regarding the effectiveness of these interventions. The purpose of this meta-analysis is to evaluate the effects of psychological interventions on depression treatment in hemodialysis patients.Methods:All randomized controlled trials (RCTs) relevant to the depression treatment of hemodialysis patients through psychological interventions were retrieved from the following databases: Embase, Pubmed, PsycINFO, the Cochrane Database of Systematic Reviews, and the Cochrane Central Register of Controlled Trials. The reference lists of identified RCTs were also screened. The Cochrane risk of bias tool was used to evaluate the quality of the studies, RevMan (5.3) was used to analyze the data, and the evidence quality of the combined results was evaluated using GRADE (3.6.1).Results:Eight RCTs were included. The combined results showed that psychological interventions significantly reduced the scores of the Beck Depression Inventory (P<0.001) and interdialysis weight gain (P<0.001). However, due to the high heterogeneity, effect size combinations of sleep quality and quality of life were not performed.Conclusion:Psychological interventions may reduce the degree of depression and improve fluid intake restriction adherence. More rigorously designed research is needed.
机译：背景：抑郁症在血液透析患者中​​非常普遍，导致患者预后不良。尽管正在为这些患者开发和使用心理干预措施，但是这些干预措施的有效性尚不确定。该荟萃分析的目的是评估心理干预对血液透析患者抑郁治疗的效果。方法：从以下数据库中检索所有与心理干预有关的血液透析患者抑郁治疗相关的随机对照试验（RCT）： ，Pubmed，PsycINFO，系统评价的Cochrane数据库以及对照试验的Cochrane中央登记册。还筛选了确定的RCT的参考清单。使用Cochrane偏倚风险工具评估研究质量，使用RevMan（5.3）分析数据，并使用GRADE（3.6.1）评估合并结果的证据质量。包括在内。综合结果表明，心理干预显着降低了贝克抑郁量表的得分（P <0.001）和透析间体重增加（P <0.001）。然而，由于异质性高，未进行睡眠质量和生活质量的影响大小组合。结论：心理干预可减少抑郁程度并改善对液体摄入的限制。需要进行更严格的设计研究。

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