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首页> 外文期刊>British journal of anaesthesia >Performance of a new pulse contour method for continuous cardiac output monitoring: validation in critically ill patients.
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Performance of a new pulse contour method for continuous cardiac output monitoring: validation in critically ill patients.

机译：用于连续心输出量监测的新型脉搏轮廓法的性能：在危重病人中的验证。

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A new calibrated pulse wave analysis method (VolumeView?/EV1000?, Edwards Lifesciences, Irvine, CA, USA) has been developed to continuously monitor cardiac output (CO). The aim of this study was to compare the performance of the VolumeView method, and of the PiCCO2? pulse contour method (Pulsion Medical Systems, Munich, Germany), with reference transpulmonary thermodilution (TPTD) CO measurements.This was a prospective, multicentre observational study performed in the surgical and interdisciplinary intensive care units of four tertiary hospitals. Seventy-two critically ill patients were monitored with a central venous catheter, and a thermistor-tipped femoral arterial VolumeView? catheter connected to the EV1000? monitor. After initial calibration by TPTD CO was continuously assessed using the VolumeView-CCO software (CCO(VolumeView)) during a 72 h period. TPTD was performed in order to obtain reference CO values (COREF). TPTD and arterial wave signals were transmitted to a PiCCO2? monitor in order to obtain CCO(PiCCO) values. CCO(VolumeView) and CCO(PiCCO) were recorded over a 5 min interval before assessment of CO(TPTD). Bland-Altman analysis, %(errors), and concordance (trend analysis) were calculated.A total of 338 matched sets of data were available for comparison. Bias for CCO(VolumeView)-CO(REF) was -0.07 litre min(-1) and for CCO(PiCCO)-CO(REF) +0.03 litre min(-1). Corresponding limits of agreement were 2.00 and 2.48 litre min(-1) (P<0.01), %(errors) 29 and 37%, respectively. Trending capabilities were comparable for both techniques.The performance of the new VolumeView?-CCO method is as reliable as the PiCCO2?-CCO pulse wave analysis in critically ill patients. However, an improved precision was observed with the VolumeView? technique. CLINICALTRIALS.GOV IDENTIFIER: NCT01405040.
机译：已经开发出一种新的校准脉搏波分析方法（VolumeView？/ EV1000 ?，美国加利福尼亚州欧文市爱德华兹生命科学公司（Edwards Lifesciences），以不断监测心输出量（CO）。这项研究的目的是比较VolumeView方法和PiCCO2的性能。脉冲轮廓法（Pulsion Medical Systems，慕尼黑，德国），采用参比经肺热稀释（TPTD）CO测量，这是在四家三级医院的外科和跨学科重症监护室进行的前瞻性，多中心观察性研究。用中心静脉导管和热敏电阻贴的股动脉VolumeView？对72位危重患者进行了监测。导管连接到EV1000？监控。通过TPTD进行初始校准后，在72小时内使用VolumeView-CCO软件（CCO（VolumeView））连续评估CO。进行TPTD以获得参考CO值（COREF）。 TPTD和动脉波信号被传输到PiCCO2？监视以获得CCO（PiCCO）值。在评估CO（TPTD）之前的5分钟内记录CCO（VolumeView）和C​​CO（PiCCO）。计算了Bland-Altman分析，％（错误）和一致性（趋势分析），总共有338套匹配的数据可供比较。 CCO（VolumeView）-CO（REF）的偏差为-0.07升min（-1），CCO（PiCCO）-CO（REF）的偏差为+0.03升min（-1）。协议的相应限制分别为2.00和2.48升min（-1）（P <0.01），％（错误）分别为29％和37％。两种技术的趋势分析能力相当。在危重病人中，新的VolumeView？-CCO方法的性能与PiCCO2？-CCO脉搏波分析一样可靠。但是，使用VolumeView观察到了更高的精度。技术。 CLINICALTRIALS.GOV标识符：NCT01405040。

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