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首页> 外文期刊>Cancer causes and control: CCC >Dietary vitamin C, E, and carotenoid intake and risk of renal cell carcinoma.
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Dietary vitamin C, E, and carotenoid intake and risk of renal cell carcinoma.

机译：饮食中维生素C，E和类胡萝卜素的摄入以及肾细胞癌的风险。

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OBJECT: The study examines the association between dietary intake of vitamin C, E, and carotenoids and the risk of renal cell carcinoma (RCC). METHODS: Between 1994 and 1997 in 8 Canadian provinces, mailed questionnaires were completed by 1,138 incident, histologically confirmed cases of RCC and 5,039 population controls, including information on socio-economic status, lifestyle habits and diet. A 69-item food frequency questionnaire provided data on eating habits 2 years before data collection. Odds ratios (OR) and 95% confidence intervals (CI) were computed using unconditional logistic regression. RESULTS: Dietary intake of beta-carotene and lutein/zeaxanthin was inversely associated with the risk of RCC. The ORs for the highest versus the lowest quartile were 0.74 (95% CI, 0.59-0.92) and 0.77 (95% CI, 0.62-0.95), respectively. The significant inverse association with beta-carotene and lutein/zeaxanthin was more pronounced in women, and in overweight or obese subjects. The relation of lutein/zeaxanthin to RCC was stronger in ever smokers. No clear association was observed with vitamin C and E, beta-cryptozanthin, and lycopene. CONCLUSION: The findings provide evidence that a diet rich in beta-carotene and lutein/zeaxanthin may play a role in RCC prevention.
机译：目的：研究检查饮食中维生素C，E和类胡萝卜素的摄入与肾细胞癌（RCC）的风险之间的关系。方法：1994年至1997年之间，在加拿大的8个省中，通过邮寄的问卷调查完成了1138例事件，组织学确诊的RCC病例和5039例人口控制，包括有关社会经济状况，生活方式和饮食的信息。一份69项食物频率调查表在收集数据前2年提供了饮食习惯数据。使用无条件逻辑回归计算赔率（OR）和95％置信区间（CI）。结果：饮食中摄入β-胡萝卜素和叶黄素/玉米黄质与RCC的发生风险呈负相关。最高四分位数与最低四分位数的OR分别为0.74（95％CI，0.59-0.92）和0.77（95％CI，0.62-0.95）。与β-胡萝卜素和叶黄素/玉米黄质的显着负相关在女性以及超重或肥胖的受试者中更为明显。叶黄素/玉米黄质与RCC的关系在吸烟者中更强。没有观察到与维生素C和E，β-隐黄质和番茄红素的明确关联。结论：这些发现提供了证据，证明富含β-胡萝卜素和叶黄素/玉米黄质的饮食可能在RCC的预防中起作用。

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