The unholy trinity: inflammation, cytokines, and STAT3 shape the cancer microenvironment.

Li N; Grivennikov SI; Karin M

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The unholy trinity: inflammation, cytokines, and STAT3 shape the cancer microenvironment.

机译：邪恶的三位一体：炎症，细胞因子和STAT3决定了癌症的微环境。

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Tumor-associated inflammation is a consequence and a driver of tumorigenesis. Three papers in this issue of Cancer Cell demonstrate the importance of tumor-elicited inflammation in the development and progression of pancreatic ductal adenocarcinoma and esophageal squamous carcinoma. Disruption of tissue homeostasis culminates in activation of STAT3, generating a pro-tumorigenic inflammatory microenvironment.

机译：肿瘤相关的炎症是后果，是肿瘤发生的驱动力。本期《癌细胞》杂志上的三篇论文证明了肿瘤引起的炎症在胰腺导管腺癌和食管鳞状细胞癌的发生和发展中的重要性。组织稳态的破坏最终导致STAT3的激活，从而产生促肿瘤的炎性微环境。

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《Cancer Cell》 |2011年第4期|共3页
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Li N; Grivennikov SI; Karin M;
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正文语种 eng
中图分类肿瘤学;
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1. The unholy trinity: inflammation, cytokines, and STAT3 shape the cancer microenvironment. [J] . Li N, Grivennikov SI, Karin M Cancer Cell . 2011,第4期

机译：邪恶的三位一体：炎症，细胞因子和STAT3决定了癌症的微环境。
2. SOCS3 Expression Correlates with Severity of Inflammation, Expression of Proinflammatory Cytokines, and Activation of STAT3 and p38 MAPK in LPS-Induced InflammationIn Vivo [J] . Jo?o Ant?nioChaves de Souza, Andressa Vilas BoasNogueira, Pedro PauloChaves de Souza, Mediators of inflammation . 2013,第1期

机译：SOCS3表达与LPS诱导的炎症体内炎症的严重程度，促炎细胞因子的表达以及STAT3和p38 MAPK的激活有关。
3. SOCS3 Expression Correlates with Severity of Inflammation, Expression of Proinflammatory Cytokines, and Activation of STAT3 and p38 MAPK in LPS-Induced Inflammation In Vivo [J] . Joao Antonio Chaves de Souza, Andressa Vilas Boas Nogueira, Pedro Paulo Chaves de Souza, Mediators of inflammation . 2013,第Pta4期

机译：SOCS3表达与LPS诱导的体内炎症的炎症程度，促炎细胞因子的表达以及STAT3和p38 MAPK的激活有关。
4. Over-activation of the stat3 pathway in lung epithelial cells induces pulmonary inflammation and lung cancer [C] . Liu Yujie, rnPiao Linhua, rnSong Jia, Journal of Organ Dysfunction: ISRD 2007 Abstract Book . 2007

机译：肺上皮细胞中stat3通路的过度激活引起肺部炎症和肺癌
5. An unholy trinity: The influence of Locke, Smith, & Keynes on British macroeconomic stabilization policy [D] . Morrison, James Ashley 2008

机译：邪恶的三位一体：洛克，史密斯和凯恩斯对英国宏观经济稳定政策的影响
6. The unholy trinity: inflammation cytokines and STAT3 shape the cancer microenvironment [O] . Ning Li, Sergei I. Grivennikov, Michael Karin -1

机译：unholy trinity：炎症细胞因子和stat3形状的癌症微环境
7. The Unholy Trinity: Inflammation, Cytokines, and STAT3 Shape The Cancer Microenvironment [O] . Li Ning, Grivennikov Sergei I., Karin Michael 2011

机译：邪恶的三位一体：炎症，细胞因子和STAT3塑造了癌症微环境

The unholy trinity: inflammation, cytokines, and STAT3 shape the cancer microenvironment.

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