Leukemia propagating cells Akt up.

Alejandro Gutierrez; Justine E Roderick; Michelle A Kelliher

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Leukemia propagating cells Akt up.

机译：白血病繁殖细胞Akt上升。

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Individual cancer cells can exhibit striking differences in tumorigenic potential following experimental transplantation, but the molecular pathways that regulate this activity remain poorly understood. In this issue of Cancer Cell, Blackburn and colleagues report that Akt signaling regulates both leukemia-propagating potential and proliferation rate via distinct pathways in T-ALL.

机译：在实验性移植后，单个癌细胞可能在致瘤潜力方面表现出惊人的差异，但调节这种活性的分子途径仍然知之甚少。在本期《癌细胞》中，Blackburn及其同事报告说，Akt信号传导通过T-ALL中的不同途径调节白血病的传播潜能和增殖速率。

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《Cancer Cell》 |2014年第3期|共3页
作者
Alejandro Gutierrez; Justine E Roderick; Michelle A Kelliher;
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正文语种 eng
中图分类肿瘤学;
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1. Leukemia propagating cells Akt up. [J] . Alejandro Gutierrez, Justine E Roderick, Michelle A Kelliher Cancer Cell . 2014,第3期

机译：白血病繁殖细胞Akt上升。
2. CD34+CD38-CD58- cells are leukemia-propagating cells in Philadelphia chromosome-positive acute lymphoblastic leukemia [J] . Y Kong, Y-J Chang, Y-R Liu, Leukemia . 2014,第12期

机译：CD34 + CD38 - CD58 -细胞是费城染色体阳性急性淋巴细胞白血病中的白血病增殖细胞
3. The side population enriches for leukemia-propagating cell activity and Wnt pathway expression in zebrafish acute lymphoblastic leukemia [J] . Jeremy T. Baeten, Michael R. Waarts, Margaret M. Pruitt, Haematologica . 2019,第7期

机译：在斑马鱼急性淋巴细胞白血病中，侧群富集了白血病传播细胞活性和Wnt途径表达
4. Color Image Enhancement of Acute Leukemia Cells in Blood Microscopic Image for Leukemia Detection Sample [C] . Nor Hazlyna Harun, Juhaida Abu Bakar, Zulkifli Abd Wahab, IEEE Symposium on Computer Applications Industrial Electronics . 2020

机译：血液白血病图像中急性白血病细胞彩色图像增强检测样本
5. The multi-targeted receptor tyrosine kinase inhibitor, linifanib (ABT-869), induces apoptosis and inhibits proliferation of leukemia cells through phosphoinositide-3 kinase (PI3K)/AKT-dependent signaling pathways. [D] . Hernandez, Jenny Elizabeth. 2010

机译：多靶点受体酪氨酸激酶抑制剂利尼法尼（ABT-869）通过磷酸肌醇3激酶（PI3K）/ AKT依赖性信号传导途径诱导凋亡并抑制白血病细胞的增殖。
6. Clonal evolution enhances leukemia propagating cell frequency in T-cell acute lymphoblastic leukemia through Akt/mTORC1 pathway activation [O] . Jessica S. Blackburn, Sali Liu, Jayme L. Wilder, -1

机译：克隆进化通过Akt / mTORC1途径激活增强T细胞急性淋巴细胞白血病中的白血病传播细胞频率
7. Clonal Evolution Enhances Leukemia-Propagating Cell Frequency in T Cell Acute Lymphoblastic Leukemia through Akt/mTORC1 Pathway Activation [O] . unknown ( host institution ), Blackburn, Jessica S. ( author ) 2014

机译：克隆进化通过Akt / mTORC1途径激活增强T细胞急性淋巴细胞白血病中的白血病传播细胞频率

Leukemia propagating cells Akt up.

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