miR-126 Drives Quiescence and Self-Renewal in Leukemic Stem Cells

Raffel Simon; Trumpp Andreas

首页> 外文期刊>Cancer Cell >miR-126 Drives Quiescence and Self-Renewal in Leukemic Stem Cells

【24h】

miR-126 Drives Quiescence and Self-Renewal in Leukemic Stem Cells

机译：miR-126驱动白血病干细胞的休眠和自我更新

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Leukemic stem cells (LSCs) are resistant to conventional chemotherapy and promote acute myeloid leukemia (AML) progression and recurrence. In this issue of Cancer Cell, Lechman and colleagues (2016) identify the microRNA miR/126 as a regulator of PI3K-AKT-mTOR and CDK3 signaling driving LSC self-renewal and chemotherapy resistance.

机译：白血病干细胞（LSC）对常规化疗有抗药性，并促进急性髓细胞白血病（AML）的进展和复发。在本期《癌细胞》中，Lechman及其同事（2016年）确定了microRNA miR / 126是PI3K-AKT-mTOR和CDK3信号的调节剂，可驱动LSC自我更新和化疗耐药。

著录项

来源
《Cancer Cell》 |2016年第2期|共4页
作者
Raffel Simon; Trumpp Andreas;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类肿瘤学;
关键词

相似文献

外文文献
中文文献
专利

1. miR-126 Drives Quiescence and Self-Renewal in Leukemic Stem Cells [J] . Raffel Simon, Trumpp Andreas Cancer Cell . 2016,第2期

机译：miR-126驱动白血病干细胞的休眠和自我更新
2. IKZF2 Drives Self-Renewal and Blocks Myeloid Differentiation Programs in Myeloid Leukemic Stem Cells [J] . Park Sun-Mi, Cho Hyunwoo, Thornton Angela, Blood: The Journal of the American Society of Hematology . 2018,第NovaelaTreatmentAppr期

机译：IKZF2驱动自我更新，并阻断骨髓性白血病干细胞中的骨髓差异化程序
3. A TIM-3/Gal-9 Autocrine Stimulatory Loop Drives Self-Renewal of Human Myeloid Leukemia Stem Cells and Leukemic Progression [J] . Kikushige Yoshikane, Miyamoto Toshihiro, Yuda Junichiro, Cell stem cell . 2015,第3期

机译：TIM-3 / Gal-9自分泌刺激环驱动人类髓样白血病干细胞自我更新和白血病进展。
4. Novel bio-inspired synthetic composite materials as promising scaffolds for stem cell-mediated tissue regeneration supporting short term self-renewal of human pluripotent stem cells in feeder-free culture conditions [C] . Maria Letizia Focarete, Chiara Gualandi, Nora Bloise, World biomaterials congress . 2016

机译：新型生物启发性合成复合材料，有望成为干细胞介导的组织再生的有希望的支架，在无饲养层的培养条件下支持人类多能干细胞的短期自我更新
5. HSC differentiation is fleeting, but self-renewal is forever: In vitro self-renewal of hematopoietic stem cells. [D] . Barria, Emily Alpas. 2004

机译：HSC分化短暂，但自我更新永远存在：造血干细胞的体外自我更新。
6. Loss of quiescence and self-renewal capacity of hematopoietic stem cell in an in vitro leukemic niche [O] . Natalia-Del Pilar Vanegas, Jean-Paul Vernot 2017

机译：体外白血病环境中造血干细胞的静态丧失和自我更新能力
7. Loss of quiescence and self-renewal capacity of hematopoietic stem cell in an in vitro leukemic niche [O] . 2017

机译：体外白血病环境中造血干细胞的静态丧失和自我更新能力
8. Purinergic Receptors in Quiescence and Localization of Leukemic Stem Cells. [R] . Lee, B. 2013

机译：嘌呤能受体在白血病干细胞静止和定位中的应用。

miR-126 Drives Quiescence and Self-Renewal in Leukemic Stem Cells

摘要

著录项

相似文献

相关主题

期刊订阅