The Future of Cancer Treatment: Will It Include Immunotherapy?

BluestoneJ.A.; SmallE.J.

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The Future of Cancer Treatment: Will It Include Immunotherapy?

机译：癌症治疗的未来：它将包括免疫疗法吗？

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Negative immune regulatory pathways inhibit anti-cancer T cell responses, preventing effective immune surveillance. Two clinical trials using monoclonal antibodies that antagonize the PD-1/PD-L1 pathway recently reported regression in several tumor types. In one of these trials, efficacy was linked to the expression of the PD-L1 biomarker on tumor cells.

机译：负性免疫调节途径抑制抗癌T细胞反应，阻止有效的免疫监视。最近有两项使用单克隆抗体拮抗PD-1 / PD-L1途径的临床试验报道了几种肿瘤类型的消退。在这些试验之一中，功效与肿瘤细胞上PD-L1生物标志物的表达有关。

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《Cancer Cell》 |2012年第1期|共2页
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BluestoneJ.A.; SmallE.J.;
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正文语种 eng
中图分类肿瘤学;
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The Future of Cancer Treatment: Will It Include Immunotherapy?

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