Location, Location, Location: Macrophage Positioning within Tumors Determines Pro- or Antitumor Activity

RiveraL.; BergersG.

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Location, Location, Location: Macrophage Positioning within Tumors Determines Pro- or Antitumor Activity

机译：位置，位置，位置：肿瘤中的巨噬细胞定位决定了前肿瘤或抗肿瘤活性

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Macrophages infiltrate hypoxic tumor regions, where they promote angiogenesis and immunosuppression. In this issue of Cancer Cell, Casazza and colleagues report that tumor-associated macrophage (TAM) entry into avascular tumor areas is regulated by Semaphorin 3A/Neuropilin-1 signaling; interference with this pathway entraps TAMs in oxygenated areas, preventing their tumorigenic function.

机译：巨噬细胞浸润缺氧肿瘤区域，它们促进血管生成和免疫抑制。在本期《癌细胞》中，Casazza及其同事报告说，与肿瘤相关的巨噬细胞（TAM）进入无血管肿瘤区域是由Semaphorin 3A / Neuropilin-1信号传导调控的。干扰该途径会使TAMs陷入氧化区域，从而阻止其致瘤功能。

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《Cancer Cell》 |2013年第6期|共3页
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RiveraL.; BergersG.;
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正文语种 eng
中图分类肿瘤学;
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1. Location, Location, Location: Macrophage Positioning within Tumors Determines Pro- or Antitumor Activity [J] . RiveraL., BergersG. Cancer Cell . 2013,第6期

机译：位置，位置，位置：肿瘤中的巨噬细胞定位决定了前肿瘤或抗肿瘤活性
2. Within-person associations of young adolescents’ physical activity across five primary locations: is there evidence of cross-location compensation? [J] . Jordan A. Carlson, Tarrah B. Mitchell, Brian E. Saelens, International Journal of Behavioral Nutrition and Physical Activity . 2017,第1期

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3. Role of tumor-associated macrophage in malignant tumors: should the location of the infiltrated macrophages be taken into account during evaluation? [J] . Ohno S, Inagawa H, Soma G, Anticancer Research: International Journal of Cancer Research and Treatment . 2002,第6C期

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4. Automated framework for estimation of lung tumor locations in kV-CBCT images for tumor-based patient positioning in stereotactic lung body radiotherapy [C] . Satoshi Yoshidome, Hidetaka Arimura, Kotaro Terashima, Conference on Physics of Medical Imaging . 2017

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5. Location, location, location: The relationship between multifamily real estate performance and location within three polycentric urban areas (Texas). [D] . Rehm, Michael James. 2002

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6. Location Location Location: Macrophage positioning within tumors determines pro-or anti-tumor activity [O] . Lee Rivera, Gabriele Bergers -1

机译：位置位置位置：肿瘤中的巨噬细胞定位决定了促肿瘤或抗肿瘤活性
7. Location, Location, Location: Macrophage Positioning within Tumors Determines Pro- or Antitumor Activity [O] . Rivera Lee B., Bergers Gabriele 2013

机译：位置，位置，位置：肿瘤中的巨噬细胞定位决定了前肿瘤或抗肿瘤活性

Location, Location, Location: Macrophage Positioning within Tumors Determines Pro- or Antitumor Activity

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