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首页> 外文期刊>Mechanisms of Ageing and Development >Glial and neuronal cell numbers and cytochrome oxidase activity in CA1 and CA3 during postnatal development and aging of the rat.
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Glial and neuronal cell numbers and cytochrome oxidase activity in CA1 and CA3 during postnatal development and aging of the rat.

机译：大鼠出生后和衰老期间，CA1和CA3中的胶质和神经元细胞数量以及细胞色素氧化酶活性。

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摘要

Stereological methods (neuron and glial cell numbers) and histochemical methods (cytochrome c oxidase) were used to study postnatal development and aging of the CA1 and CA3 hippocampal areas in male rats. No changes were observed in 10 microns sections in the neuronal population of areas CA1 and CA3 in any of the groups (14 days, 21 days, adult-90 days and elderly-22 months). Statistical differences were found in the number of glial cells in both the CA1 and CA3 areas. An increase was observed in cytochrome oxidase (CO) activity in the CA1 area in the 14 day old rats compared to the other groups while in area CA3 this parameter increased in the 14 and 21 day old groups and the group of adult rats. No significant changes in CO activity were found in the elderly rats in both areas. These results are discussed in the light of those recorded in other areas of the limbic system.
机译：使用体视学方法（神经元和神经胶质细胞数）和组织化学方法（细胞色素C氧化酶）研究雄性大鼠CA1和CA3海马区的产后发育和衰老。在任何一组（14天，21天，成人90天和老年人22个月）中，CA1和CA3区神经元群体的10微米切片均未观察到变化。在CA1和CA3区域的神经胶质细胞数量上发现统计学差异。与其他组相比，在14天龄大鼠的CA1区域中观察到细胞色素氧化酶（CO）活性增加，而在CA3区，14天和21天龄的组以及成年大鼠组中该参数增加。在这两个地区的老年大鼠中，未发现CO活性的显着变化。根据边缘系统其他区域中记录的结果讨论了这些结果。

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