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首页> 外文期刊>International journal of urology: official journal of the Japanese Urological Association >Effects of sextant transrectal prostate biopsy plus additional far lateral cores in improving cancer detection rates in men with large prostate glands.
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Effects of sextant transrectal prostate biopsy plus additional far lateral cores in improving cancer detection rates in men with large prostate glands.

机译：六分经直肠前列腺活检加上其他远侧核对提高男性大前列腺癌检出率的影响。

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摘要

PURPOSE: To determine whether additional, far lateral cores improve the diagnostic performance of transrectal sextant biopsy in men with large prostate glands. METHODS: Men with prostate volumes of 50 mL or greater in transrectal ultrasonography who were suspected of prostatic adenocarcinoma were prospectively enrolled. Biopsy criteria were defined as 2.0 ng/mL or greater of serum total prostate-specific antigen and/or abnormal findings on digital rectal examination. Four cores of far lateral biopsies were added to the standard sextant technique. RESULTS: Of 104 patients enrolled in the present study and undergoing biopsy, 14 (13.5%) were diagnosed as having prostate cancer and 27 (26.0%) were diagnosed as having prostatic intraepithelial neoplasia (PIN) or an atypical gland. There were no cases where cancer was only detected in the additional cores, whereas PIN/atypical gland was uniquely detected from the additional, far lateral sites in eight of the 27 patients who were diagnosed with this condition. CONCLUSIONS: Although the number of patients diagnosed as having PIN/atypical gland might increase with the addition of far lateral cores, this additional sampling does not improve cancer detection rates in men with large prostate glands.
机译：目的：确定额外的远侧核是否可以改善男性前列腺大的经直肠六分切活检的诊断性能。方法：前瞻性研究经直肠超声检查前列腺容积大于或等于50 mL的男性，怀疑前列腺癌。活检标准定义为血清总前列腺特异性抗原和/或直肠指检异常发现为2.0 ng / mL或更高。将远侧活检的四个核心添加到标准六分仪技术中。结果：本研究招募的104例活检患者中，有14例（13.5％）被诊断为前列腺癌，27例（26.0％）被诊断为前列腺上皮内瘤变（PIN）或非典型腺体。没有病例仅在附加核中检测到癌症，而在被诊断出患有此病的27例患者中，有8例从附加的远侧部位独特地检测到PIN /非典型腺体。结论：尽管增加了远侧核，被诊断为PIN /非典型腺体的患者数量可能会增加，但是这种额外的采样并不能提高患有大前列腺的男性的癌症检出率。

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