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Papillomavirus vaccine coverage and its determinants in South-Eastern France

机译：东南法国的乳头瘤病毒疫苗覆盖率及其决定因素

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Objectives: We wanted: (i) to assess vaccine coverage (VC) for papillomavirus (HPV) (one and three doses of the vaccine, VC1 and VC3) and compliance with the recommended vaccination regimen (3rd dose within 1. year after the 1st dose) among 14-16 year-old girls; and (ii) to identify the factors independently associated with VC and compliance with the recommended vaccination regimen. Methods: We conducted a descriptive longitudinal study, using the National Health Insurance reimbursement database, for years 2007 to 2009, in South-Eastern France. We performed a multivariate analysis (Cox proportional hazards model). Results: VC1 was 35.5%, with 68.8% of those who started vaccination having completed the 3-dose regimen, 64.1% within one year. VC1 and VC3 were positively associated with the girl's age. Girls covered by the complementary social welfare healthcare program and those living in rural areas had lower VC1 and VC3. Being covered by the complementary social welfare healthcare program was also associated with lower compliance with the recommended vaccination regimen. VC1 and VC3 were positively associated with the number of medical consultations during the study period. Important geographical variations were noted regarding VC1. Conclusions: Our study confirms that VC for HPV is insufficient in our region, and that there are socio-economic and geographical inequalities. Even though the vaccine is reimbursed for all girls, efforts must be made to improve VC, particularly for girls covered by the complementary social welfare healthcare program and those living in rural areas.
机译：目标：我们希望：（i）评估乳头瘤病毒（HPV）的疫苗覆盖率（VC）（一剂和三剂疫苗VC1和VC3），并符合推荐的疫苗接种方案（第一剂后一年内的第三剂）。剂量）在14-16岁的女孩中; （ii）确定与VC独立相关的因素以及是否符合建议的疫苗接种方案。方法：我们使用国家健康保险报销数据库在法国东南部2007年至2009年进行了描述性的纵向研究。我们进行了多元分析（Cox比例风险模型）。结果：VC1为35.5％，其中开始接种疫苗的68.8％的人已完成3剂方案，一年内达到64.1％。 VC1和VC3与女孩的年龄呈正相关。由补充性社会福利保健计划覆盖的女孩和农村地区的女孩的VC1和VC3较低。被补充的社会福利医疗保健计划覆盖的原因还在于对建议的疫苗接种方案的依从性较低。在研究期间，VC1和VC3与医疗咨询次数呈正相关。注意到有关VC1的重要地理差异。结论：我们的研究证实，在我们地区，用于HPV的VC不足，并且存在社会经济和地理上的不平等。即使为所有女孩都报销了这种疫苗，也必须努力改善风湿病，特别是对那些由补充社会福利医疗计划覆盖的女孩和农村地区的女孩。

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