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首页> 外文期刊>International journal of urology: official journal of the Japanese Urological Association >Outcome analysis for conservative management of Peyronie's disease.
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Outcome analysis for conservative management of Peyronie's disease.

机译：保守治疗佩罗尼氏病的结果分析。

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BACKGROUND: We retrospectively analysed the outcomes of conservative management of Peyronie's disease and determined the factors predicting successful outcome. METHODS: The study involved 31 patients with Peyronie's disease who were treated at our institute between 1985 and 2003. We assessed the efficacy of vitamin E for the improvement of the symptoms, and the factors which contributed to successful outcome with conservative management using multivariate analysis. RESULTS: There was no statistically significant difference in the relief rate between the vitamin E and no-medication groups. The overall estimated relief rate was 67.5% at 2 years from presentation. The multivariate analysis revealed plaque size to be the only significant factor predicting the relief from all symptoms in patients with conservative management. The rate was 100% in patients having a plaque size of 20 mm or smaller and 20.0% in those having a size of larger than 20 mm (P=0.005). CONCLUSIONS: We could not confirm the benefit of vitamin E for Peyronie's disease. Plaque size was the only significant factor predicting the relief from all symptoms. Patients with larger plaque might fail to respond to the conservative management.
机译：背景：我们回顾性分析了佩罗尼氏病保守治疗的结果，并确定了预测成功结果的因素。方法：该研究纳入了1985年至2003年间在我院接受治疗的31例佩罗尼氏病患者。我们使用多因素分析评估了维生素E改善症状的功效，以及保守治疗成功促成因素。结果：维生素E组和非药物治疗组的缓解率无统计学差异。出现后2年的总体估计缓解率为67.5％。多元分析表明，斑块大小是预测保守治疗患者所有症状缓解的唯一重要因素。斑块大小小于或等于20 mm的患者的发生率为100％，而斑块大小大于20 mm的患者为20.0％（P = 0.005）。结论：我们无法确定维生素E对佩罗尼氏病的益处。斑块大小是预测所有症状缓解的唯一重要因素。斑块较大的患者可能对保守治疗无反应。

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