THYMINE AUXOTROPHY IS ASSOCIATED WITH INCREASED UV SENSITIVITY IN ESCHERICHIA COLI AND BACILLUS SUBTILIS

Lojo MM

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THYMINE AUXOTROPHY IS ASSOCIATED WITH INCREASED UV SENSITIVITY IN ESCHERICHIA COLI AND BACILLUS SUBTILIS

机译：胸腺萎缩症与大肠埃希氏菌和芽胞杆菌的紫外线敏感性增加有关

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Thymine auxotrophy was shown to be associated with an increase in UV sensitivity both in Bacillus subtilis and in Escherichia coli. This UV sensitization became clearly evident in polA5 mutants of Bacillus subtilis: at UV doses of 16 J/m(2), a reduction of more than 10-fold in the survivor population is observed in thymine requiring spontaneous mutants (polA5 thyA thyB) compared to the parental strains (polA5). Reversion of either thyA or thyB mutation led to a partial recovery in the UV resistance. This result suggests that DNA repair polymerization might be improved by the biosynthesis of thymidylate or some effect associated with such activity.

机译：在枯草芽孢杆菌和大肠杆菌中，胸腺嘧啶营养缺陷症均与紫外线敏感性增加有关。这种紫外线敏化作用在枯草芽孢杆菌的polA5突变体中变得很明显：在紫外线剂量为16 J / m（2）时，在需要自发突变体的胸腺嘧啶中观察到幸存者的数量减少了10倍以上（polA5 thyA thyB）亲本菌株（polA5）。 thyA或thyB突变的逆转导致抗紫外线性部分恢复。该结果表明，可以通过胸苷酸的生物合成或与这种活性相关的某些作用来改善DNA修复聚合。

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《Mutation Research, C. Mutation Research Letters》 |1995年第1期|共6页
作者
Lojo MM;
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正文语种 eng
中图分类遗传学;
关键词
Escherichia coil; Bacillus subtilis; Uv sensitivity; Pola; Thymidine; Dna repair; System; Reductase; Linkage; Enzymes; Complex;

机译：大肠杆菌;枯草芽孢杆菌;Uv敏感性;Pola;胸腺嘧啶;Dna修复;系统;还原酶;连锁;酶;复合物;

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专利

1. Thymine auxotrophy is associated with increased UV sensitivity in Escherichia coli and Bacillus subtilis. [J] . Lojo MM Mutation Research: International Journal on Mutagenesis, Chromosome Breakage and Related Subjects . 1995,第1期

机译：胸腺嘧啶营养缺陷型与大肠杆菌和枯草芽孢杆菌对紫外线的敏感性增加有关。
2. Roles of YqjH and YqjW, Homologs of the Escherichia coli UmuC/DinB or Y Superfamily of DNA Polymerases, in Stationary-Phase Mutagenesis and UV-Induced Mutagenesis of Bacillus subtilis [J] . Huang-Mo Sung, Gabriel Yeamans, Christian A. Ross, Journal of bacteriology . 2003,第7期

机译：YqjH和YqjW，大肠杆菌UmuC / DinB的同源物或DNA聚合酶的Y超家族在枯草芽孢杆菌的固定相诱变和紫外线诱导诱变中的作用
3. UV-induced crosslinks in the 16S rRNAs of Escherichia coli, Bacillus subtilis and Thermus aquaticus and their implications for ribosome structure and photochemistry [J] . James W. Noah, Tatjana Shapkina, Paul Wollenzien Nucleic Acids Research . 2000,第19期

机译：紫外线诱导的大肠杆菌，枯草芽孢杆菌和水生栖热菌16S rRNA中的交联及其对核糖体结构和光化学的影响
4. Reconciliation of Regulatory Data: The Regulatory Networks of Escherichia coli and Bacillus subtilis [C] . Diogo Lima, Fernando Cruz, Miguel Rocha, International Conference on Practical Applications of Computational Biology Bioinformatics . 2021

机译：监管数据的和解：大肠杆菌和枯草芽孢杆菌的监管网络
5. Production of 2,3-butanediol in Escherichia coli and Bacillus subtilis [D] . Rodrigues De Oliveira, Rafael 2014

机译：在大肠杆菌和枯草芽孢杆菌中生产2,3-丁二醇
6. Roles of YqjH and YqjW Homologs of the Escherichia coli UmuC/DinB or Y Superfamily of DNA Polymerases in Stationary-Phase Mutagenesis and UV-Induced Mutagenesis of Bacillus subtilis [O] . Huang-Mo Sung, Gabriel Yeamans, Christian A. Ross, 2003

机译：YqjH和YqjW大肠杆菌UmuC / DinB的同系物或DNA聚合酶的Y超家族的作用在枯草芽孢杆菌的固定相诱变和紫外线诱导的诱变中
7. AKTIVITAS ANTIBAKTERI PROTEIN KAPANG Xylaria psidii KT30 TERHADAP Escherichia coli DAN Bacillus subtilis [Antibacterial Activity of Protein Fungus Xylaria psidii KT30 on Escherichia coli and Bacillus subtilis] [O] . Aris Munandar1,2), A. Zaenal Mustopa3), Kustiariyah Tarman2)*, 2014

机译：aKTIVITas aNTIBaKTERI蛋白质KapaNG Xylaria psidii KT30 TERHaDap大肠杆菌DaN枯草芽孢杆菌[蛋白质真菌Xylaria psidii KT30对大肠杆菌和枯草芽孢杆菌的抗菌活性]

THYMINE AUXOTROPHY IS ASSOCIATED WITH INCREASED UV SENSITIVITY IN ESCHERICHIA COLI AND BACILLUS SUBTILIS

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