COMPARATIVE STUDY OF SCE INDUCTION AND CYTOSTATIC EFFECTS BY HOMO-AZASTEROIDAL ESTERS OF N,N-BIS(2-CHLOROETHYL) AMINOBENZOIC ACID IN HUMAN LYMPHOCYTES

Mourelatos D; Mylonaki E; Papageorgiou A; Boutis L; Paradelis A

首页> 外文期刊>Mutation Research, C. Mutation Research Letters >COMPARATIVE STUDY OF SCE INDUCTION AND CYTOSTATIC EFFECTS BY HOMO-AZASTEROIDAL ESTERS OF N,N-BIS(2-CHLOROETHYL) AMINOBENZOIC ACID IN HUMAN LYMPHOCYTES

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COMPARATIVE STUDY OF SCE INDUCTION AND CYTOSTATIC EFFECTS BY HOMO-AZASTEROIDAL ESTERS OF N,N-BIS(2-CHLOROETHYL) AMINOBENZOIC ACID IN HUMAN LYMPHOCYTES

机译：N，N-双-（2-氯乙基）氨基苯甲酸在人淋巴球中均氮-恒芳酯的SCE诱导和细胞抑制作用的比较研究

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The effect of homo-azasteroidal esters of benzoic acid mustard isomers and the 4-methyl derivatives, which have steroidal lactams as a biological basis, on cytogenetic damage was studied. Twenty compounds were comparatively studied, on a molar basis, as regards their ability to induce sister-chromatid exchanges (SCEs) and cell division delays.

机译：研究了以甾族内酰胺为生物学基础的苯甲酸芥子异构体的均氮氮类固醇酯和4-甲基衍生物对细胞遗传学损伤的影响。在摩尔基础上，对二十种化合物诱导姐妹染色单体交换（SCE）和细胞分裂延迟的能力进行了比较研究。

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《Mutation Research, C. Mutation Research Letters》 |1995年第3期|共5页
作者
Mourelatos D; Mylonaki E; Papageorgiou A; Boutis L; Paradelis A;
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正文语种 eng
中图分类遗传学;
关键词
Homo azasteroidal ester of benzoic acid mustard isomers; Sister chromatid; Chromatid exchange assay; Invivo; Cells; Prediction; Invitro; Damage;

机译：苯甲酸芥子异构体的均氮类甾醇酯;染色单体染色;染色单体交换测定;体内;细胞;预测;体外;损伤;

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1. Comparative study of SCE induction and cytostatic effects by homo-azasteroidal esters of N,N-bis(2-chloroethyl)aminobenzoic acid in human lymphocytes. [J] . Mourelatos D, Mylonaki E, Papageorgiou A, Mutation Research: International Journal on Mutagenesis, Chromosome Breakage and Related Subjects . 1995,第3期

机译：N，N-双（2-氯乙基）氨基苯甲酸同氮氮类固醇酯在人淋巴细胞中对SCE诱导和抑制细胞生长作用的比较研究。
2. Structure-antileukemic activity relationship study of B- and D-ring modified and nonmodified steroidal esters of 4-methyl-3-N,N-bis(2-chloroethyl)amino benzoic acid: a comparative study. [J] . Fousteris MA, Koutsourea AI, Arsenou ES, Anti-cancer drugs . 2007,第9期

机译：B和D环修饰和未修饰的4-甲基-3-N，N-双（2-氯乙基）氨基苯甲酸甾体酯的结构-抗酮活性关系研究：对比研究。
3. ON THE FORMATION OF ESTRONE LACTAM ESTERS OF N,N-BIS(2-CHLOROETHYL)AMINOCINNAMIC ACID ISOMERS, P-N,N-BIS(2-CHLOROETHYL)AMINOPHENYLBUTYRIC ACID AND THEIR ANTITUMOR ACTIVITY [J] . Catsoulacos P., Papageorgiou A., Pairas G. Journal of Heterocyclic Chemistry: The International Journal of Heterocyclic Chemistry . 1995,第3期

机译：N，N-BIS（2-氯乙基）氨基辛酸异构体，P-N，N-BIS（2-氯乙基）氨基苯甲酸丁二酸内酯酯的形成及其反义活性
4. Genotoxicity induction by Multi-Walled Carbon Nanotubes interacting with Humic acids in cultured human lymphocytes [C] . M-S Vidali, E Bletsa, GC Skoutelis The Meeting of the International Humic Substances Society . 2015

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机译：由葡萄球菌肠毒素B和佛波醇酯通过诱导肿瘤坏死因子α来抑制无症状HIV-1携带者的CD8 + T淋巴细胞介导的人类免疫缺陷病毒1型（HIV-1）复制的体外抑制。
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8. Results of 2 Algal Studies, a Daphnid and Fish Study, Eye Irritation and Skin Sensitization Studies, an In Vitro Ames Assay in Salmonella and a Chromosomal Aberration Assay in Human Peripheral Blood Lymphocytes with Benzoic Acid, 2(chlorosulfonyl)-3-Methyl and Methyl Ester. [R] . 2009

机译：2种藻类研究，水蚤和鱼类研究，眼睛刺激和皮肤致敏研究的结果，沙门氏菌的体外ames测定和人类外周血淋巴细胞中的染色体畸变测定，苯甲酸，2（氯磺酰基）-3-甲基和甲基酯。

COMPARATIVE STUDY OF SCE INDUCTION AND CYTOSTATIC EFFECTS BY HOMO-AZASTEROIDAL ESTERS OF N,N-BIS(2-CHLOROETHYL) AMINOBENZOIC ACID IN HUMAN LYMPHOCYTES

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