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首页> 外文期刊>Cardiology in review >Importance of medication adherence in cardiovascular disease and the value of once-daily treatment regimens.
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Importance of medication adherence in cardiovascular disease and the value of once-daily treatment regimens.

机译：依从性在心血管疾病中的重要性以及每天一次治疗方案的价值。

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摘要

An estimated 71 million individuals in the United States are currently diagnosed with cardiovascular disease (CVD). If untreated, CVD conditions such as systemic hypertension, coronary artery disease, and heart failure will have potentially serious and often fatal outcomes. Numerous clinical trials have established a variety of evidence-based medications that are efficacious in the treatment of CVD. These drugs will be ineffective, however, if patients have trouble adhering to their prescribed regimens. In patients with hypertension or heart failure, or in those who have suffered a myocardial infarction, poor adherence to therapies has been linked to a variety of problems, including poor blood pressure control, rehospitalization, and increased healthcare resource utilization. Both the asymptomatic nature of some forms of CVD and the high pill burden associated with certain therapies have been linked to poor adherence. Reducing pill burden through the use of once-daily formulations has proven valuable in improving adherence to evidence-based therapies. This review will discuss the impact of adherence to prescribed therapies for CVD, outline common barriers to adherence, and demonstrate the value of once-daily dosing regimens for improved patient adherence.
机译：目前，在美国估计有7100万人被诊断出患有心血管疾病（CVD）。如果不加以治疗，CVD疾病（例如全身性高血压，冠状动脉疾病和心力衰竭）将有潜在的严重后果，甚至可能致命。许多临床试验已经建立了多种可有效治疗CVD的循证药物。但是，如果患者在遵守处方药方面遇到困难，这些药物将无效。在患有高血压或心力衰竭的患者中，或在患有心肌梗塞的患者中，对治疗的依从性差会导致许多问题，包括血压控制不佳，再次住院和医疗资源利用率提高。某些形式的CVD的无症状性质和与某些疗法相关的高药丸负担都与依从性差有关。事实证明，通过每天使用一次制剂来减轻药丸负担，对于改善对循证疗法的依从性具有重要意义。这篇综述将讨论坚持CVD处方疗法的影响，概述坚持坚持的常见障碍，并证明每天一次给药方案对改善患者依从性的价值。

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