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首页> 外文期刊>Cancer radiotherapie: journal de la Soci閠?fran鏰ise de radiotherapie oncologique >Radiotherapy for non-small-cell bronchial cancers: definitions of volumes, patient selection. Recommendations of the International Association for the Study of Lung Cancer (IASLC)
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Radiotherapy for non-small-cell bronchial cancers: definitions of volumes, patient selection. Recommendations of the International Association for the Study of Lung Cancer (IASLC)

机译:非小细胞支气管癌的放射治疗:体积定义,患者选择。国际肺癌研究协会(IASLC)的建议

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摘要

Chemoradiation is the standard treatment of unresectable, locally advanced non-small cell lung cancer, with a mean dose of 60-66 Gy, excluding escalation dose schemes. The standard treated volume includes primary tumor, ipsilateral hilar and mediastinal nodes, supraclavicular and contralateral nodes as well, regardless of the node status. This work tries to answer the question of the optimal volume to be treated. Drainage routes analysis is in favor of large volumes, while toxicity analysis favors small volumes. Combined modality treatment may increase the observed toxicity. The optimal volume definition is difficult, and requires available conformal therapy tools. Patients selection is another important issue. A volume definition is then attempted, based on the IASLC (International Association for the Study of Lung Cancer) Annecy workshop experience, highlighting the interobservers discrepancies, and suggests basic recommendations to harmonize volume definition.
机译:化学放疗是不可切除的局部晚期非小细胞肺癌的标准治疗方法,平均剂量为60-66 Gy,不包括逐步升级剂量方案。标准治疗体积包括原发肿瘤,同侧肺门和纵隔淋巴结,锁骨上和对侧淋巴结,无论淋巴结状态如何。这项工作试图回答要治疗的最佳量的问题。排水路线分析倾向于大体积,而毒性分析则倾向于小体积。联合方式治疗可能会增加观察到的毒性。最佳的体积定义是困难的,并且需要可用的保形治疗工具。患者选择是另一个重要问题。然后,根据IASLC(国际肺癌研究协会)阿讷西研讨会的经验,尝试进行体积定义,强调观察者之间的差异,并提出统一体积定义的基本建议。

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