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Scalable fabrication of immunosensors based on carbon nanotube polymer composites

机译:基于碳纳米管聚合物复合材料的免疫传感器的可扩展制造

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In this work we present the fabrication and characterization of immunosensors based on polystyrene (PS)-multiwalled carbon nanotube (MWCNT) composites. The electrochemical properties of the sensors have been investigated and show that the surface area is increased upon addition of the MWCNT-PS layer. Furthermore, a plasma activation process is used to partially remove the PS and expose the MWCNTs. This results in a huge increase in the electrochemical area and opens up the possibility of binding biomolecules to the MWCNT wall. The MWCNTs have been functionalized covalently with a model antibody (rabbit IgG). The biosensors have been tested using amperometric techniques and show detection limits comparable to standard techniques such as ELISA.
机译:在这项工作中,我们介绍了基于聚苯乙烯(PS)-多壁碳纳米管(MWCNT)复合材料的免疫传感器的制备和表征。已经对传感器的电化学性质进行了研究,结果表明,在添加MWCNT-PS层后,表面积会增加。此外,使用等离子体活化工艺来部分去除PS并暴露MWCNT。这导致电化学面积的巨大增加,并打开了将生物分子与MWCNT壁结合的可能性。 MWCNT已通过模型抗体(兔IgG)共价官能化。生物传感器已使用安培技术进行了测试,并显示出与标准技术(例如ELISA)相当的检测极限。

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