pH-sensitive intracellular photoluminescence of carbon nanotube–fluorescein conjugates in human ovarian cancer cells

M T Chen; L M Gomez; F N Ishikawa; P T Vernier; C Zhou; M A Gundersen

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pH-sensitive intracellular photoluminescence of carbon nanotube–fluorescein conjugates in human ovarian cancer cells

机译：pH敏感的碳纳米管-荧光素结合物在人卵巢癌细胞中的细胞内发光

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To add to the understanding of the properties of functionalized carbon nanotubes in biological applications, we report a monotonic pH sensitivity of the intracellular fluorescence emission of single-walled carbon nanotube—fluorescein carbazide (SWCNT—FC) conjugates in human ovarian cancer cells. Light-stimulated intracellular hydrolysis of the amide linkage and localized intracellular pH changes are proposed as mechanisms. SWCNT—FC conjugates may serve as intracellular pH sensors.

机译：为了加深对功能化碳纳米管在生物学应用中特性的理解，我们报道了单壁碳纳米管-荧光素脲（SWCNT-FC）缀合物在人卵巢癌细胞中的细胞内荧光发射的单调pH敏感性。酰胺键的光刺激细胞内水解和局部细胞内pH变化被认为是机制。 SWCNT-FC共轭物可以用作细胞内pH传感器。

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《Nanotechnology》 |2009年第29期|共7页
作者
M T Chen; L M Gomez; F N Ishikawa; P T Vernier; C Zhou; M A Gundersen;
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正文语种 eng
中图分类 710C0161;
关键词
photoluminescence; carbon; human ovarian cancer cells;

机译：光致发光;碳;人卵巢癌细胞;

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专利

1. pH-sensitive intracellular photoluminescence of carbon nanotube–fluorescein conjugates in human ovarian cancer cells [J] . M T Chen, L M Gomez, F N Ishikawa, Nanotechnology . 2009,第29期

机译：pH敏感的碳纳米管-荧光素结合物在人卵巢癌细胞中的细胞内发光
2. Augmented anticancer activity of a targeted, intracellularly activatable, theranostic nanomedicine based on fluorescent and radiolabeled, methotrexate-folic acid-multiwalled carbon nanotube conjugate [J] . DasM., DatirS.R., SinghR.P., Molecular pharmaceutics . 2013,第7期

机译：基于荧光和放射性标记的甲氨蝶呤-叶酸-多壁碳纳米管共轭物的靶向，细胞内可活化的治疗性纳米药物的增强的抗癌活性
3. Fabrication, Characterization, and Functionalization of Single-Walled Carbon Nanotube Conjugated with Tamoxifen and Its Anticancer Potential against Human Breast Cancer Cells [J] . Arshin Oskoueian, Khamirul Amin Matori, Saadi Bayat, Journal of nanomaterials . 2018,第Pta1期

机译：用三氧肟缀合的单壁碳纳米管的制造，表征和官能化及其对人乳腺癌细胞的抗癌潜力
4. Cellular Uptake of Carbon Nanotubes Conjugated to Semiconductor Quantum Dots for Breast Cancer Imaging and Treatment Applications [C] . Kristen A. Zimmermann, Jianfei Zhang, Harry Dorn, ASME summer bioengineering conference;SBC2010 . 2010

机译：碳纳米管与半导体量子点共轭的细胞吸收在乳腺癌成像和治疗应用中的应用
5. The roles of aryl hydrocarbon receptor in human fetoplacental endothelial cells and ovarian cancer. [D] . Li, Yan. 2015

机译：芳基烃受体在人胎盘内皮细胞和卵巢癌中的作用。
6. pH-sensitive Photoluminescence of CdSe/ZnSe/ZnS Quantum Dots in Human Ovarian Cancer Cells [O] . Yu-San Liu, Yinghua Sun, P. Thomas Vernier, -1

机译：CdSe / ZnSe / ZnS量子点在人卵巢癌细胞中的pH敏感光致发光
7. pH-Sensitive Photoluminescence of CdSe/ZnSe/ZnS Quantum Dots in Human Ovarian Cancer Cells [O] . Yu-San Liu, Yinghua Sun, P. Thomas Vernier, 2007

机译：人卵巢癌细胞中CDSE / ZnSE / ZnS量子点的pH敏感的光致发光

pH-sensitive intracellular photoluminescence of carbon nanotube–fluorescein conjugates in human ovarian cancer cells

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