• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Nanotechnology >Selective growth of silica nanowires using an Au catalyst for optical recognition of interleukin-10
【24h】

Selective growth of silica nanowires using an Au catalyst for optical recognition of interleukin-10

机译：使用Au催化剂选择性生长二氧化硅纳米线以光学识别白介素10

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The vapor-liquid-solid (VLS) growth procedure has been extended for the selective growth of silica nanowires on SiO2 layer by using Au as a catalyst. The nanowires were grown in an open tube furnace at 1100 degrees C for 60 min using Ar as a carrier gas. The average diameter of these bottom-up nucleated wires was found to be 200 nm. Transmission electron microscopy analysis indicates the amorphous nature of these nanoscale wires and suggests an Si-silica heterostructure. The localized silica nanowires have been used as an immunoassay template in the detection of interleukin-10 which is a lung cancer biomarker. Such a nanostructured platform offered a tenfold enhancement in the optical response, aiding the recognition of IL-10 in comparison to a bare silica substrate. The role of nanowires in the immunoassay was verified through the quenching behavior in the photoluminescence (PL) spectra. Two orders of reduction in PL intensity have been observed after completion of the immunoassay with significant quenching after executing every stEP 2of the protocol. The potential of this site-specific growth of silica nanowires on SiO2 as a multi-modal biosensing platform has been discussed.
机译：气液固（VLS）生长过程已扩展为通过使用Au作为催化剂在SiO2层上选择性生长二氧化硅纳米线。使用Ar作为载气，将纳米线在1100摄氏度的开放式管式炉中生长60分钟。这些自下而上的有核线的平均直径被发现为200nm。透射电子显微镜分析表明这些纳米级线的无定形性质，并表明硅-二氧化硅异质结构。本地化的二氧化硅纳米线已被用作免疫测定模板，用于检测作为肺癌生物标志物的白介素10。这种纳米结构平台在光学响应方面提供了十倍的增强，与裸露的二氧化硅基质相比，有助于识别IL-10。纳米线在免疫测定中的作用已通过光致发光（PL）光谱中的猝灭行为进行了验证。免疫分析完成后，观察到PL强度下降了两个数量级，在执行方案的每个stEP 2后均显着淬灭。已经讨论了二氧化硅纳米线在SiO2上作为多模式生物传感平台的特定于位点生长的潜力。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号