An Easy Way to Pyrimidine Based Nucleoterpenes

Serena Fiorito; Salvatore Genovese; Francesco Epifano

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An Easy Way to Pyrimidine Based Nucleoterpenes

机译：一种基于嘧啶的核萜的简便方法

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The direct synthesis of N~3 substituted pyrimidine nucleoterpenes from uridine, thymidine, and inosine with C5, C10, and C15 side chains and using DBU as the base is described. In all cases the reaction proceeded smoothly in very good yields (85-99%) affording selectively N~3 substituted adducts.

机译：描述了由尿苷，胸苷和肌苷通过C5，C10和C15侧链直接合成N〜3取代的嘧啶核萜，并以DBU为基础。在所有情况下，反应均以非常好的收率（85-99％）顺利进行，提供了选择性的N〜3个取代的加合物。

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《Natural product communications》 |2014年第6期|共3页
作者
Serena Fiorito; Salvatore Genovese; Francesco Epifano;
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正文语种 eng
中图分类自然科学总论;
关键词
N-prenyl compounds; Nucleoterpenes; Oligonucleotides; Prenylation.;

机译：N-异戊烯基化合物;核萜;寡核苷酸;异戊二烯化。;

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1. An Easy Way to Pyrimidine Based Nucleoterpenes [J] . Serena Fiorito, Salvatore Genovese, Francesco Epifano Natural product communications . 2014,第6期

机译：一种基于嘧啶的核萜的简便方法
2. SYNTHESIS OF THIAZOLO [3,2-a]PYRIMIDINES BASED ON 4-ARYL-SUBSTITUTED 3,4-DIHYDRO-PYRIMIDINE(1H)-2-THIONES AND THE CRYSTAL STRUCTURE OF ETHYL 5-(2,4-DIMETHOXYPHENYL)-7-METHYL-3-OXO-3,5-DIHYDRO-2H-THIAZOLO-[3,2-a] PYRIMIDINE-6-CARBOXYLATE [J] . I. V. Kulakov, O.A.Nurkenov, D. M. Turdybekov, Chemistry of heterocyclic compounds . 2009,第7期

机译：基于4-芳基取代的3,4-二氢嘧啶（1H）-2-亚硫基噻唑并[3,2-a]嘧啶的合成及乙基5-（2,4-二甲氧基苯）-7-的晶体结构甲基-3-OXO-3,5-二氢-2H-噻唑基-[3,2-a]嘧啶-6-羧酸盐
3. Thermodynamic investigations on derivatives of pyrimidine nucleic acid bases - Joint use of calorimetric, volumetric and structural data for the description of properties of pyrimidine nucleic acid bases and their derivatives [J] . Zielenkiewicz W. Thermochimica Acta: An International Journal Concerned with the Broader Aspects of Thermochemistry and Its Applications to Chemical Problems . 2003,第1期

机译：嘧啶核酸碱基衍生物的热力学研究-结合使用量热，体积和结构数据描述嘧啶核酸碱基及其衍生物的性质
4. Pyrimidine based dyes embedded in porous silicon microcavities for detection of nitroaromatic compounds [C] . Igor L. Martynov, Evgeniy V. Osipov, Yriy A. Kuzishchin, Conference on Counterterrorism, Crime Fighting, Forensics, and Surveillance Technologies . 2019

机译：基于嘧啶的染料嵌入多孔硅片微胶囊中，用于检测硝基芳族化合物
5. Design and Synthesis of Pyrimidine Based Heterocycles as Potential Anti-cancer Agents with Combination Chemotherapeutic Potential or Targeted One Carbon Metabolism Inhibition and Anti-opportunistic Agents [D] . Doshi, Arpit. 2019

机译：基于嘧啶的杂环作为潜在抗癌剂的设计与合成，具有组合化疗潜力或靶向一种碳代谢抑制和抗机会性药物
6. Strong specific monodentate G-C base pair recognition by N7-inosine derivatives in the pyrimidine.purine-pyrimidine triple-helical binding motif. [O] . J Marfurt, S P Parel, C J Leumann 1997

机译：在嘧啶。嘌呤-嘧啶三螺旋结合基序中被N7-肌苷衍生物强烈特异性单齿G-C碱基对识别。
7. Cover Feature: Synthesis of Mono- and Bis(fluoroalkyl)pyrimidines from FARs, Fluorinated Acetoacetates, and Malononitrile Provides Easy Access to Novel High-Value Pyrimidine Scaffolds (Chem. Eur. J. 6/2018) [O] . Etienne Schmitt, Bruno Commare, Armen Panossian, 2017

机译：覆盖特征：合成来自FARS，氟化乙酰乙酸酯和丙二酸的单烷基和双（氟代烷基）嘧啶，可容易地进入新型高价值嘧啶脚手架（Chem.Eur。J. 6/2018）
8. NMR Structural Studies on a Nonnatural Deoxyribonucleoside Mediated Recognitionof GC Base Pairs in Pyrimidine-Purine-Pyrimidine Triplexes [R] . Radhakrishnan, I., Patel, D. J., Priestley, E. S., 1993

机译：核苷酸结构研究非天然脱氧核糖核苷介导的嘧啶 - 嘌呤 - 嘧啶三联体GC碱基对的识别

An Easy Way to Pyrimidine Based Nucleoterpenes

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