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Comparative Chemical Study and Cytotoxic Activity of Uvariodendron angustifolium Essential Oils from Benin

机译:贝宁乌头杜鹃花精油的化学比较研究和细胞毒活性

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摘要

This study aimed to compare the chemical composition of volatile extracts obtained by hydrodistillation of leaves, stems, bark and roots of Uvariodendron angustifolium (Engl. & Diels) R. E. Fries. The essential oils, obtained with yields between 0.12 and 0.66%, were analyzed by GC/FID and GC/MS. A great variability in the chemical composition was observed depending on the plant part treated. The essential oils obtained from leaves and stems contained mainly neral (29.7-30.5%) and geranial (42.9-47.3%), while methyl eugenol was the major component of the volatile extracts from bark (68.3%) and roots (85.3%). Interesting cytotoxic properties of these essential oils on human breast cancer cells MCF-7 were demonstrated.
机译:这项研究的目的是比较挥发油提取物的化学成分,该挥发物提取物通过对乌贼木叶,茎,树皮和根进行水蒸馏而得到。通过GC / FID和GC / MS分析了收率在0.12%至0.66%之间的精油。根据所处理的植物部位,观察到化学组成的巨大变化。从叶和茎中获得的香精油主要含有神经(29.7-30.5%)和香叶醛(42.9-47.3%),而甲基丁香酚是树皮(68.3%)和根(85.3%)的挥发性提取物的主要成分。这些精油对人乳腺癌细胞MCF-7的有趣的细胞毒性特性得到了证实。

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