A Novel C21 Cyclopentenone Derivative from Cipadessa cinerascens

Zhang Jing; Chang Yao-Wen; Yuan Chun-Mao; Zhang Fan; Di Ying-Tong; Hao Xiao-Jiang

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A Novel C21 Cyclopentenone Derivative from Cipadessa cinerascens

机译：Cipadessa cinerascens的新型C21环戊烯酮衍生物

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摘要

A new C-21 cyclopentenone derivative, Cipacyclonone (1), was isolated from the leaves of Cipadessa cinerascens. Its structure was elucidated on the basis of spectroscopic analysis, including extensive ID- and 2D-NMR techniques. Compound 1 showed strong cytotoxicity activity against HL-60 and A-549 cell lines, with IC50 values of 1.2 and 3.0 mu M, respectively.

机译：从Cipadessa cinerascens的叶子中分离出一种新的C-21环戊烯酮衍生物Cipacyclonone（1）。在光谱分析的基础上阐明了其结构，包括广泛的1D和2D-NMR技术。化合物1显示出对HL-60和A-549细胞系的强细胞毒性活性，IC 50值分别为1.2和3.0μM。

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《Natural product communications》 |2015年第8期|共2页
作者
Zhang Jing; Chang Yao-Wen; Yuan Chun-Mao; Zhang Fan; Di Ying-Tong; Hao Xiao-Jiang;
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正文语种 eng
中图分类自然科学总论;
关键词
Cipadessa cinerascens; Meliaceae; Cyclopentenone; Cipacyclonone;

机译：Cipadessa cinerascens;M科;环戊烯酮;Cipacyclonone;

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1. A Novel C21 Cyclopentenone Derivative from Cipadessa cinerascens [J] . Zhang Jing, Chang Yao-Wen, Yuan Chun-Mao, Natural product communications . 2015,第8期

机译：Cipadessa cinerascens的新型C21环戊烯酮衍生物
2. Cipacinoids A-D, Four Limonoids with Spirocyclic Skeletons from Cipadessa cinerascens [J] . Yu Jin-Hai, Liu Qun-Fang, Sheng Li, Organic letters . 2016,第3期

机译：Cipacinoids A-D，四个柠檬环的柠檬苦素，来自Cipadessa cinerascens
3. Limonoids with Anti-HIV Activity from Cipadessa cinerascens [J] . Yu Jin-Hai, Wang Guo-Cai, Han Ying-Shan, Journal of natural products . 2015,第6期

机译：Cipadessa cinerascens具有抗HIV活性的柠檬苦素
4. Hydroxyalkyl derivatives of cyclopentenone obtained under Baylis Hillman conditions using more environmentally friendly catalysts [C] . Krassimira P. Guerra, Carlos A. M. Afonso European Symposium on Organic Chemistry . 2009

机译：使用更多环保型催化剂在Baylis Hillman条件下获得环戊烯酮的羟烷基衍生物
5. Responses of leaf gas exchange to environmental variation in two widely dispersed Juniperus species versus a narrowly restricted endemic, Petrophytum cinerascens (Juniperus occidentalis, J. osteosperma). [D] . Moore, Darrin John. 1998

机译：与两种狭窄分布的地方性灰质Petroptum cinerascens（Juniperus occidentalis，J.osteosperma）相比，两种广泛分布的杜松属植物叶片气体交换对环境变化的响应。
6. Cipatrijugin G a new trijugin-type limonoid bearing an uncommon γ-hydroxybutenolide unit from the aerial parts of Cipadessa cinerascens [O] . Cheng-Shi Jiang, Yan Li, Zhen-Zhong Wang, 2013

机译：Cipatrijugin G一种新的Trijugin型柠檬苦素带有来自Cipadessa cinerascens空中部分的罕见γ-羟基丁烯内酯单元
7. Cipatrijugin G, a new trijugin-type limonoid bearing an uncommon γ-hydroxybutenolide unit from the aerial parts of Cipadessa cinerascens [O] . Cheng-Shi Jiang, Yan Li, Zhen-Zhong Wang, 2013

机译：Cipatrijugin G，一种新的Trijugin型柠檬苦素，带有来自Cipadessa cinerascens空中部分的罕见γ-羟基丁烯内酯单元
8. Compaction Control of a Major Construction Project with the Michigan Nuclear Gage US 127 Relocation, Holt Road to I 96 (F 33035B, C1; Bi 33084A, C21) [R] . DeFoe, J. H., Mainfort, R. C. 1966

机译：使用密歇根核电计美国127重新安置的主要建筑项目的压实控制，Holt Road至I 96（F 33035B，C1; Bi 33084a，C21）

A Novel C21 Cyclopentenone Derivative from Cipadessa cinerascens

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