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Chemical composition, antimicrobial and antioxidant properties of the volatile oil and methanol extract of xenophyllum poposum

机译:Xenophyllum poposum挥发油和甲醇提取物的化学组成,抗菌和抗氧化性能。

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摘要

The essential oil and methanol extract of northwestern Argentina medicinal plant Xenophyllum poposum, collected in Catamarca province, were investigated. GC and GC-MS analyses of the essential oil identified 56 compounds accounting for 92.9%. The main components of the oil were δ-cadinene (16.5%), 6-hydroxytremetone (14.7%), epi-α-cadinol (12.0%), α-cadinol (8.8%), γ-cadinene (7.5%), 1-epi-cubenol (4.2%) and α-muurolene (3.0%). The essential oil exhibited antibacterial activities against five pathogenic strains as well as antifungal activities against two pathogenic fungi. The methanol extract showed antibacterial activity against two strains of Staphylococcus aureus and two pathogenic fungal strains. The main components isolated from the methanol extract were the antifungal 4-hydroxy-3-(isopenten-2- yl)-acetophenone, 6-hydroxytremetone, and tremetone. 6-Hydroxytremetone showed activity against all the fungal strains and one of the S. aureus strains assayed. Antioxidant and radical-scavenging properties of the methanol extract and essential oil were determined using the 2,2'-diphenyl-1-picrylhydrazyl assay and β-carotene bleaching (BCB) test. The methanol extract and the essential oil showed, respectively, moderate and weak antioxidant activity when compared to butylated hydroxytoluene.
机译:调查了在卡塔马卡省采集的阿根廷西北部药用植物Xenophyllum poposum的精油和甲醇提取物。精油的GC和GC-MS分析确定了56种化合物,占92.9%。该油的主要成分是δ-卡丁烯(16.5%),6-羟基聚丁酮(14.7%),epi-α-cadinol(12.0%),α-cadinol(8.8%),γ-cadinene(7.5%),1 -表古苯酚(4.2%)和α-茂苯(3.0%)。精油对五种病原菌表现出抗菌活性,对两种病原真菌表现出抗真菌活性。甲醇提取物对两种金黄色葡萄球菌菌株和两种病原性真菌菌株均具有抗菌活性。从甲醇提取物中分离出的主要成分是抗真菌的4-羟基-3-(异戊二烯-2-基)-苯乙酮,6-羟基聚丁酮和聚丁酮。 6-羟基维甲酸显示出对所有真菌菌株和其中一种金黄色葡萄球菌菌株的活性。甲醇提取物和香精油的抗氧化和清除自由基的性能使用2,2'-二苯基-1-吡啶并肼基测定法和β-胡萝卜素漂白(BCB)试验测定。与丁基化羟基甲苯相比,甲醇提取物和香精油分别显示出中等和较弱的抗氧化活性。

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