...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Nephrology, dialysis, transplantation: official publication of the European Dialysis and Transplant Association - European Renal Association >Late nephrology referral and mortality among patients with end-stage renal disease: a propensity score analysis.
【24h】

Late nephrology referral and mortality among patients with end-stage renal disease: a propensity score analysis.

机译：晚期肾病患者的晚期肾病转诊和死亡率：倾向评分分析。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BACKGROUND: Late nephrology referral has been associated with adverse outcomes among patients with end-stage renal disease; however, its relationship to mortality is unclear. We examined the impact of timing of nephrology care relative to initiation of dialysis on mortality after initiation of dialysis. METHODS: Data from the Dialysis Morbidity and Mortality Study - Wave II, a prospective study of incident dialysis patients, were used. Late referral (LR) was defined as first nephrology visit <4 months and early referral (ER) as first nephrology visit >or=4 months prior to initiation of dialysis. Propensity scores (PS) were estimated using logistic regression to predict the probability that a given patient was LR. A Cox proportional hazards model was built to examine the association between timing of nephrology referral and mortality. RESULTS: The cohort was comprised of 2195 patients: 54% were males, 66% were Caucasians, 26% were African-Americans and 33% were referred late. A Cox proportional hazards analysis demonstrated that compared with ER patients, LR patients had a 44% higher risk of death at 1 year after initiation of dialysis [hazards ratio (HR) = 1.44; 95% confidence interval (CI): 1.15-1.80], which remained significant after adjusting for quintiles of PS (HR = 1.42; 95% CI: 1.12-1.80). CONCLUSIONS: Among patients with chronic kidney disease (CKD) who initiated dialysis, LR was associated with higher risk of death at 1 year after initiation of dialysis compared with ER.
机译：背景：晚期肾脏病患者转诊晚期肾病与不良预后相关。但是，它与死亡率的关系尚不清楚。我们检查了透析开始时相对于透析开始时间的肾脏病护理对死亡率的影响。方法：使用来自透析发病率和死亡率研究的数据-Wave II，这是一项针对透析患者的前瞻性研究。晚期转诊（LR）定义为开始透析前<4个月的首次肾脏病就诊，而早期转诊（ER）定义为开始透析前≥4个月的首次肾病就诊。使用逻辑回归来估计倾向得分（PS），以预测给定患者为LR的可能性。建立了Cox比例风险模型以检查肾脏病转诊时间与死亡率之间的关联。结果：该队列包括2195名患者：男性54％，白种人66％，非裔美国人26％，晚期转诊33％。 Cox比例风险分析表明，与ER患者相比，LR患者在开始透析后1年的死亡风险高44％[风险比（HR）= 1.44; 95％置信区间（CI）：1.15-1.80]，在调整了PS的五分位数后，该区间仍然很显着（HR = 1.42; 95％CI：1.12-1.80）。结论：在开始透析的慢性肾脏病（CKD）患者中，与ER相比，LR与透析开始后1年的死亡风险更高。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号