Cytotoxic compounds of Physena madagascariensis from the Madagascar rain forest paragraph sign.

Cao S; Norris A; Miller JS; Ratovoson F; Birkinshaw C; Andriantsiferana R; Rasamison VE; Rakotonandrasana S; Kingston DG

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Cytotoxic compounds of Physena madagascariensis from the Madagascar rain forest paragraph sign.

机译：来自马达加斯加雨林段落标志的马达加斯加Phys生理毒性化合物。

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Two new flavanones, remangiflavanones D and E (1 and 2), were isolated from an extract of the twigs, leaves, and flowers of Physena madagascariensis together with three known flavanones, remangiflavanones A-C (3-5), and (E)-N-feruloyltyramine (6). The structures of the new compounds 1 and 2 were established on the basis of one-dimensional and two-dimensional NMR spectroscopic data interpretation. All compounds were evaluated for their cytotoxicity in the A2780 human ovarian cancer cell line. Compound 5 was the most active with an IC50 value of 2.5 microg mL-1.

机译：从猕猴桃（Physena madagascariensis）的树枝，叶子和花朵的提取物中分离出两种新的黄烷酮，remangiflavanones D和E（1和2），以及三种已知的黄烷酮，remangiflavanones AC（3-5）和（E）-N -feruloyltyramine（6）。基于一维和二维NMR光谱数据解释，建立了新化合物1和2的结构。评估所有化合物在A2780人卵巢癌细胞系中的细胞毒性。化合物5的活性最高，IC50值为2.5微克mL-1。

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《Natural product research》 |2006年第13期|共7页
作者
Cao S; Norris A; Miller JS; Ratovoson F; Birkinshaw C; Andriantsiferana R; Rasamison VE; Rakotonandrasana S; Kingston DG;
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正文语种 eng
中图分类数理科学和化学;
关键词
Caryophyllaceae; Cytotoxins; Flavanones; Plant Extracts; 细胞毒素类; 植物提取物;

机译：Caryophyllaceae;Cytotoxins;Flavanones;Plant Extracts;细胞毒素类;植物提取物;

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1. Cytotoxic compounds of Physena madagascariensis from the Madagascar rain forest paragraph sign. [J] . Cao S, Norris A, Miller JS, Natural product research . 2006,第13期

机译：来自马达加斯加雨林段落标志的马达加斯加Phys生理毒性化合物。
2. Cytotoxic diterpenoids from Podocarpus madagascariensis from the Madagascar rainforest. [J] . Reynolds M, Chaturvedula VS, Ratovoson F, Natural product research . 2006,第6期

机译：来自马达加斯加雨林的罗汉松（Podocarpus madagascariensis）的细胞毒性二萜。
3. Cytotoxic and other compounds from Didymochlaena truncatula from the Madagascar rain forest. [J] . Cao S, Radwan MM, Norris A, Journal of natural products . 2006,第2期

机译：来自马达加斯加雨林的Didymochlaena truncatula的细胞毒性和其他化合物。
4. Characterization of cytotoxic compound from marine sediment derived new actinomycete Streptomyces coelicolor strain SU5 [C] . Sudha. S, Masilamani Selvam. M Green Technology and Environmental Conservation (GTEC 2011), 2011 International Conference on . 2011

机译：来自海洋沉积物的新放线菌链霉菌coelicolor菌株SU5的细胞毒性化合物的表征
5. Isolation and structure determination of bioactive natural products from Physena madagascariensis and the design and synthesis of 24-nortriterpene analogues. [D] . Deng, Yonghong. 2001

机译：马达加斯加Phys（Physena madagascariensis）生物活性天然产物的分离和结构测定，以及24-降三萜类似物的设计和合成。
6. Cytotoxic and Other Compounds from Didymochlaena truncatula from the Madagascar Rain Forest [O] . Shugeng Cao, Mohamed M. Radwan, Andrew Norris, -1

机译：来自马达加斯加雨林的Did草的细胞毒性和其他化合物
7. Cytotoxic and Other Compounds from Didymochlaena truncatula from the Madagascar Rain Forest [O] . -1

机译：来自马达加斯加雨林的迪尤霍纳特·丁德纳的细胞毒性和其他化合物

Cytotoxic compounds of Physena madagascariensis from the Madagascar rain forest paragraph sign.

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