Bladder cancer: Predicting response to BCG.

Payton S

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Bladder cancer: Predicting response to BCG.

机译：膀胱癌：预测对BCG的反应。

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Methylation status of a select panel of genes can predict failure of bacillus Calmette-Guerin (BCG) immunotherapy, according to research carried out by Marta Sanchez-Carbayo and colleagues at the Spanish National Cancer Research Centre in Madrid. Intravesical BCG is the treatment of choice for patients with non-muscle-invasive bladder cancer who are considered to be at high risk of recurrence and progression to muscle-invasive disease. However, about a third of recipients do not respond to BCG, and the ability to identify which patients might require more-aggressive management is a major goal of bladder cancer research today.

机译：根据马德里西班牙国家癌症研究中心的Marta Sanchez-Carbayo及其同事进行的研究，选择的一组基因的甲基化状态可以预测卡介苗-卡林芽孢杆菌（BCG）免疫疗法的失败。膀胱内BCG是非肌肉浸润性膀胱癌患者的首选治疗方法，这些患者被认为具有复发和发展为肌肉浸润性疾病的高风险。但是，约有三分之一的接受者对BCG没有反应，而确定哪些患者可能需要更积极治疗的能力是当今膀胱癌研究的主要目标。

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《Nature reviews. Urology》 |2011年第7期|共1页
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Payton S;
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中图分类泌尿科学（泌尿生殖系疾病）;
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1. Bladder cancer: Predicting response to BCG. [J] . Payton S Nature reviews. Urology . 2011,第7期

机译：膀胱癌：预测对BCG的反应。
2. Nomograms predicting response to therapy and outcomes after bladder-preserving trimodality therapy for muscle-invasive bladder cancer [J] . CoenJ.J., PalyJ.J., NiemierkoA., International Journal of Radiation Oncology, Biology, Physics . 2013,第2期

机译：线型图预测保留肌肉的三联疗法治疗肌肉浸润性膀胱癌后对治疗的反应和结果
3. The predictive value of GSTT1 polymorphisms in predicting the early response to induction BCG therapy in patients with non-muscle invasive bladder cancer [J] . KangH.W., TcheyD.-U., YanC., Urologic oncology . 2014,第4期

机译：GSTT1基因多态性在预测非肌肉浸润性膀胱癌患者对诱导BCG治疗的早期反应中的预测价值
4. Predictive Biomarkers for Neoadjuvant Chemotherapy Response in Muscle-Invasive Bladder Cancer: A survey [C] . Hisham Abdeltawab, Fahmi Khalifa, Mohammed Ghazal, IEEE International Symposium on Signal Processing and Information Technology . 2018

机译：肌肉浸润性膀胱癌新辅助化疗反应的预测性生物标志物：一项调查
5. Cystoscopy and the development of invasive bladder cancer in patients presenting with superficial urinary bladder cancer. [D] . Amos, Charles E., Jr. 2003

机译：膀胱镜检查和浅表性膀胱癌患者的浸润性膀胱癌的发展。
6. Predicting response of bladder cancers to gemcitabine and carboplatin neoadjuvant chemotherapy through genome-wide gene expression profiling [O] . YOICHIRO KATO, HITOSHI ZEMBUTSU, RYO TAKATA, -1

机译：通过全基因组基因表达谱预测膀胱癌对吉西他滨和卡铂新辅助化疗的反应
7. Accounting for B cell behaviour and sampling bias yields a superior predictor of anti-PD-L1 response in bladder cancer [O] . I.A. Dyugay, D.K. Lukyanov, M.A. Turchaninova, 2021

机译：B细胞行为和抽样偏压的核算产生了膀胱癌的抗PD-L1反应的优越预测因子

Bladder cancer: Predicting response to BCG.

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