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首页> 外文期刊>Nature reviews. Urology >Paediatrics: to screen or not to screen--the role of VCUG in infant UTI.
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Paediatrics: to screen or not to screen--the role of VCUG in infant UTI.

机译：儿科：筛查或不筛查VCUG在婴儿UTI中的作用。

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摘要

Prostate cancer incidence and mortality in most native Asian populations have gradually increased, but are around one-third lower than in corresponding Asian-American cohorts, which are themselves lower than the rates observed in other American cohorts. Although genetic and environmental factors, particularly a Western diet, could partially explain these differences, lower exposure to PSA screening in Asian individuals might be a major contributing factor. Genetic features and diet are, however, unlikely to differ substantially within the same region of Asia, and age-stratified PSA levels in men from various Asian countries are almost identical; therefore, variation in the epidemiology of prostate cancer among native Asian populations might be attributable to differences in access to PSA testing, urology clinics, and available therapies. Conversely, the proportion of patients with metastatic prostate cancer is substantially higher even in the more developed Asian countries than in migratory Asian populations residing in Western countries and in Westerners. Consequently, the most appropriate approaches to the management of prostate cancer in Asian countries probably also differ, and therefore individualized prostate cancer screening and treatment strategies based on the epidemiological features and socioeconomic status of each country are needed.
机译：在大多数亚洲土著人口中，前列腺癌的发病率和死亡率已逐渐增加，但比相应的亚裔美国人队列低约三分之一，而亚裔美国人队列本身也低于其他美洲队列中观察到的比率。尽管遗传和环境因素（尤其是西方饮食）可以部分解释这些差异，但亚洲人降低PSA筛查的暴露量可能是主要因素。然而，在亚洲同一地区，遗传特征和饮食差异不大，而且来自亚洲各个国家的男性按年龄分层的PSA水平几乎相同。因此，亚洲本地人口中前列腺癌的流行病学差异可能归因于PSA检测，泌尿科门诊和可用疗法的获取差异。相反，即使在较发达的亚洲国家中，转移性前列腺癌患者的比例也大大高于居住在西方国家和西方人中的亚洲移徙人口。因此，亚洲国家中最合适的前列腺癌管理方法也可能有所不同，因此需要根据每个国家的流行病学特征和社会经济状况进行个性化的前列腺癌筛查和治疗策略。

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