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首页> 外文期刊>Neoplasma: Journal of Experimental and Clinical Oncology >Fine-needle aspiration biopsy of cervical lymph nodes: factors in predicting malignant diagnosis.
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Fine-needle aspiration biopsy of cervical lymph nodes: factors in predicting malignant diagnosis.

机译：宫颈淋巴结细针穿刺活检：预测恶性诊断的因素。

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>The objective of the study was to determine the predicting factors in malignant diagnosis in ultrasonography guided fine-needle aspiration biopsy of cervical lymph nodes. Design is retrospective follow-up study. Ultrasonography guided fine-needle aspiration biopsies of cervical lymph nodes were performed in 290 patients. The mean age was 45.5+/-14.4 years (range; 15-85). 207 (71.4%) and 83 (28.6%) were women and men, respectively. Cytopathologist was not present in any biopsy procedure. Factors in predicting malignancy were age, gender, presence of primary malignancy, localization (Level 1-6), hypoechogenicity with loss of echogenic hilum, microcalcification, cystic feature, minimum and maximum sizes, and index value (minimum size/maximum size). Factors were analyzed by univariate and multivariable tests. The mean minimum size and index value of the lymph nodes were 10.4+/-5.5 mm and 0.58+/-0.18, respectively. Age, gender, microcalcification, cystic feature, minimum size, and index value were poor predictors in malignancy. >Predictors were presence of primary malignancy (p-< 0.001), the level of localization (p=0.001), and hypoechogenicity (p-< 0.001)- in malignancy. Microcalcification and cystic parts were specific US findings of metastasis of thyroid carcinoma; nevertheless cystic parts were seen more specific finding in the other malignancies. Malignant lymph nodes were often found in the presence of primary malignancy, mid neck and lower neck localizations as Level 3-6, and markedly hypoechoic lymph nodes. In 131 patients with a primary thyroid carcinoma, the predictors for malignancy were localization where the most often regions were Level 3, 4, and 6 and hypoechogenicity. Malignancy rate was relatively low in patients with thyroid malignancy than those with non thyroid malignancies in Level 5. Level 6 was the most difficult area for biopsy due to postoperative changes. Microcalcification was specific only in thyroid carcinoma, whereas cystic parts were more specific in the other malignancies. Keywords: Fine-needle aspiration biopsy; cervical; neck; lymph node; malignancy.
机译：>该研究的目的是确定在超声引导下宫颈淋巴结细针穿刺活检中恶性诊断的预测因素。设计是回顾性随访研究。 290例患者接受了超声引导下的颈部淋巴结细针穿刺活检。平均年龄为45.5 +/- 14.4岁（范围; 15-85岁）。妇女和男子分别为207（71.4％）和83（28.6％）。没有任何活检过程中存在细胞病理学家。预测恶性肿瘤的因素是年龄，性别，原发性恶性肿瘤的存在，定位（1-6级），回声丧失的低回声性，微钙化，囊性特征，最小和最大尺寸以及指标值（最小尺寸/最大尺寸）。通过单变量和多变量检验分析因素。淋巴结的平均最小大小和指数值分别为10.4 +/- 5.5 mm和0.58 +/- 0.18。年龄，性别，微钙化，囊性特征，最小尺寸和指数值是恶性肿瘤的不良预测指标。 >预测因素包括原发性恶性肿瘤（p- <0.001），定位水平（p = 0.001）和低回声性（p- <0.001）-。微钙化和囊性部位是甲状腺癌转移的美国特异表现;然而，在其他恶性肿瘤中发现囊性部分更为特异性。恶性淋巴结常存在于原发性恶性肿瘤，颈中部和下颈的局限性水平为3-6，并且明显为低回声淋巴结。在131例原发性甲状腺癌患者中，恶性肿瘤的预测因素是定位，最常见的区域是3、4、6级和低回声性。甲状腺恶性肿瘤患者的恶性率在第5级中比非甲状腺恶性肿瘤低。由于术后改变，第6级是活检最困难的区域。微钙化仅在甲状腺癌中具有特异性，而在其他恶性肿瘤中囊性部分则更具特异性。宫颈颈部;淋巴结;恶性肿瘤。

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