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首页> 外文期刊>Neoplasma: Journal of Experimental and Clinical Oncology >Prediction of survival and cancer recurrence using F-18 FDG PET/CT in patients with surgically resected early stage (Stage I and II) non-small cell lung cancer.
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Prediction of survival and cancer recurrence using F-18 FDG PET/CT in patients with surgically resected early stage (Stage I and II) non-small cell lung cancer.

机译：使用F-18 FDG PET / CT对患有手术切除的早期（I和II期）非小细胞肺癌患者的生存率和癌症复发率进行预测。

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摘要

The aim of the current study was to investigate the prognostic value of SUVmax in patients with completely resected early stage (stage I and II) NSCLC.
A retrospective review identified 76 patients with surgically resected early (stage I and II) NSCLC who received F-18 FDG PET/CT at diagnosis of cancer. Survival analysis was conducted using Kaplan-Meier analysis, and survival curves stratified by age, sex, mediastinal lymph node involvement, SUVmax, and TNM staging were generated for estimation of overall survival and disease free survival (DFS). Independent predictive factors for survival were determined using Cox proportional hazard model.
For overall survival, the median survival of the patients with tumor SUVmax6.7 (Log rank test, Chi2=18.01, p5.9. The median survival of the patients with tumor SUVmaxIn conclusion, high FDG uptake measured by F-18 FDG PET/CT might have a prognostic value for overall survival and DFS in surgically resected early stage (stage I and II) NSCLC even after stratified by pathologic stages. Keywords: F-18 FDG, Early stage, non-small cell lung cancer, overall survival, disease free survival.
机译：本研究的目的是调查SUVmax在完全切除的早期（I和II期）NSCLC患者中的预后价值。
一项回顾性研究确定了76例早期切除的（I和II期）NSCLC患者。在诊断癌症时接受F-18 FDG PET / CT的人。使用Kaplan-Meier分析进行生存分析，并生成按年龄，性别，纵隔淋巴结受累，SUVmax和TNM分期分层的生存曲线，以评估总体生存和无病生存（DFS）。使用Cox比例风险模型确定生存的独立预测因素。
就整体生存而言，肿瘤SUVmax 6.7的患者（对数秩检验，Chi2 = 18.01，p5.9。） SUVmax 结论：用F-18 FDG PET / CT测量的高FDG摄取可能具有F-18 FDG早期非小细胞肺癌整体生存率，无病生存期对F-18 FDG早期手术切除的早期（I和II期）NSCLC患者总生存率和DFS的预后价值。

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