Structure of the sucrose-specific porin ScrY from Salmonella typhimurium and its complex with sucrose

Forst D.; Wacker T.; Diederichs K.; Welte W.

首页> 外文期刊>Nature structural biology >Structure of the sucrose-specific porin ScrY from Salmonella typhimurium and its complex with sucrose

【24h】

Structure of the sucrose-specific porin ScrY from Salmonella typhimurium and its complex with sucrose

机译：鼠伤寒沙门氏菌蔗糖特异性孔蛋白ScrY的结构及其与蔗糖的复合物

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The X-ray structure of a sucrose-specific porin (ScrY) from Salmonella typhimurium has been determined by multiple isomorphous replacement at 2.4 Angstrom resolution both in its uncomplexed form and with bound sucrose. ScrY is a noncrystallographic trimer of identical subunits, each with 413 structurally well-defined amino acids. A monomer is built up of 18 anti-parallel beta-strands surrounding a hydrophilic pore, with a topology closely similar to that of maltoporin. Two non-overlapping sucrose-binding sites were identified in difference Fourier maps. The higher permeability for sucrose of ScrY as compared to maltoporin is mainly accounted for by differences in their pore-lining residues. [References: 79]

机译：鼠伤寒沙门氏菌的蔗糖特异性孔蛋白（ScrY）的X射线结构已通过在2.4埃分辨率下以其未络合形式和结合蔗糖的多种同构置换确定。 ScrY是相同亚基的非晶体三聚体，每个亚基具有413个结构明确的氨基酸。单体由围绕亲水孔的18条反平行β链组成，其拓扑结构与麦托泊林极为相似。在差异傅立叶图中鉴定出两个不重叠的蔗糖结合位点。与麦芽酚素相比，ScrY的蔗糖渗透性更高，这主要是由于它们的孔衬残基不同所致。 [参考：79]

著录项

来源
《Nature structural biology》 |1998年第1期|共10页
作者
Forst D.; Wacker T.; Diederichs K.; Welte W.;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类生物科学;
关键词
Mannose-binding protein; Gram-negative bacteria; Outer-membrane porin; Escherichia-coli; Molecular architecture; Angstrom resolution; Electrostatic interactions; Sugar translocation; Maltoporin channels; Crystal-structures;

机译：甘露糖结合蛋白;革兰氏阴性菌;外膜孔蛋白;大肠埃希菌;分子结构;埃解析度;静电相互作用;糖易位;麦托泊林通道;晶体结构;

相似文献

外文文献
中文文献
专利

1. Structure of the sucrose-specific porin ScrY from Salmonella typhimurium and its complex with sucrose [J] . Forst D., Wacker T., Diederichs K., Nature structural biology . 1998,第1期

机译：鼠伤寒沙门氏菌蔗糖特异性孔蛋白ScrY的结构及其与蔗糖的复合物
2. Immunochemical structure of the OmpD porin from Salmonella typhimurium [J] . Shiva P. Singh, Stephanie Miller, Yvonne U. Williams, Microbiology . 1996,第11期

机译：来自沙门氏菌的OMPD Porin的免疫化学结构
3. The three-dimensional structures of nicotinate mononucleotide:5,6- dimethylbenzimidazole phosphoribosyltransferase (CobT) from Salmonella typhimurium complexed with 5,6-dimethybenzimidazole and its reaction products determined to 1.9 A resolution. [J] . Cheong CG, Escalante Semerena-JC, Rayment I Biochemistry . 1999,第49期

机译：鼠伤寒沙门氏菌与5,6-二甲基苯并咪唑复合的烟酸酯单核苷酸：5,6-二甲基苯并咪唑磷酸核糖基转移酶（CobT）的三维结构及其反应产物确定为1.9 A分辨率。
4. Evaluation of Salmonella Typhimurium fecal shedding in pigs vaccinated with Salmonella Choleraesuis-Typhimurium vaccine via drinking water and challenged four weeks later [C] . Q. Steichen, R. A. Smiley, B. Fergen, Annual^Meeting of the American^Association^of^Swine^Veterinarians. . 2016

机译：评价猪沙门氏菌育鼠粪便患者在饮用水中用沙门氏菌胆管疫苗疫苗接种疫苗，并挑战四周后
5. Structure and assembly of the flagellar hook-basal body complex of Salmonella typhimurium. [D] . Jones, Christopher John. 1989

机译：鼠伤寒沙门氏菌鞭毛钩基体复合物的结构和组装。
6. Crystal structure of the dimer of two essential Salmonella typhimurium proteins YgjD YeaZ and calorimetric evidence for the formation of a ternary YgjD–YeaZ–YjeE complex [O] . C E Nichols, HK Lamb, P Thompson, 2013

机译：两种必需的鼠伤寒沙门氏菌蛋白YgjD和YeaZ的二聚体的晶体结构以及形成三元YgjD–YeaZ–YjeE复合物的量热证据
7. Structure of the sucrose-specific porin ScrY from Salmonella typhimurium and its complex with sucrose [O] . Doris Forst, Wolfram Welte, Thomas Wacker, 1998

机译：来自沙门氏菌的蔗糖特异性茯苓的结构及其与蔗糖的复合物
8. Design and Implementation of a Collaborative Study of the Mutagenicity of Complex Mixtures in 'Salmonella typhimurium' [R] . Lewtas, J., Claxton, L. D., Rosenkranz, H. S., 1992

机译：“鼠伤寒沙门氏菌”复合混合物致突变性协同研究的设计与实施

Structure of the sucrose-specific porin ScrY from Salmonella typhimurium and its complex with sucrose

摘要

著录项

相似文献

相关主题

期刊订阅