Nuclear magnetic relaxation dispersion profiles of substantia nigra pars compacta in Parkinson's disease patients are consistent with protein aggregation.

Lopiano L; Fasano M; Giraudo S; Digilio G; Koenig SH; Torre E; Bergamasco B; Aime S

首页> 外文期刊>Neurochemistry International: The International Journal for the Rapid Publication of Critical Reviews, Preliminary and Original Research Communications in Neurochemistry >Nuclear magnetic relaxation dispersion profiles of substantia nigra pars compacta in Parkinson's disease patients are consistent with protein aggregation.

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Nuclear magnetic relaxation dispersion profiles of substantia nigra pars compacta in Parkinson's disease patients are consistent with protein aggregation.

机译：帕金森氏病患者黑质致密部黑质的核磁弛豫分布与蛋白质聚集相符。

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Nuclear Magnetic Relaxation field-cycling relaxometry is a technique, able to report on water mobility in tissues. By means of this technique, post-mortem specimens from both controls and idiopathic Parkinson's disease patients have been investigated. Results show different relaxometric behavior between the groups, which is consistent with protein aggregation in Parkinson's disease specimens.

机译：核磁弛豫场循环弛豫法是一项能够报告组织中水流动性的技术。通过这种技术，已经研究了来自对照和特发性帕金森氏病患者的验尸标本。结果显示两组之间的弛豫行为不同，这与帕金森氏病标本中的蛋白质聚集一致。

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《Neurochemistry International: The International Journal for the Rapid Publication of Critical Reviews, Preliminary and Original Research Communications in Neurochemistry》 |2000年第4期|共6页
作者
Lopiano L; Fasano M; Giraudo S; Digilio G; Koenig SH; Torre E; Bergamasco B; Aime S;
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正文语种 eng
中图分类生物化学;
关键词
Nerve Tissue Proteins; Nuclear Magnetic Resonance; Parkinson Disease; Substantia Nigra; 神经组织蛋白质类; 核磁共振; 帕金森病; 黑质;

机译：Nerve Tissue Proteins;Nuclear Magnetic Resonance;Parkinson Disease;Substantia Nigra;神经组织蛋白质类;核磁共振;帕金森病;黑质;

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1. Nuclear magnetic relaxation dispersion profiles of substantia nigra pars compacta in Parkinson's disease patients are consistent with protein aggregation. [J] . Lopiano L, Fasano M, Giraudo S, Neurochemistry International: The International Journal for the Rapid Publication of Critical Reviews, Preliminary and Original Research Communications in Neurochemistry . 2000,第4期

机译：帕金森氏病患者黑质致密部黑质的核磁弛豫分布与蛋白质聚集相符。
2. 3D neuromelanin-sensitive magnetic resonance imaging with semi-automated volume measurement of the substantia nigra pars compacta for diagnosis of Parkinson’s disease [J] . Kimihiro Ogisu, Kohsuke Kudo, Makoto Sasaki, Neuroradiology . 2013,第6期

机译：3D神经黑色素敏感的磁共振成像，可对黑质致密部进行半自动体积测量，以诊断帕金森氏病
3. 3D neuromelanin-sensitive magnetic resonance imaging with semi-automated volume measurement of the substantia nigra pars compacta for diagnosis of Parkinson's disease [J] . OgisuK., KudoK., SasakiM., Neuroradiology . 2013,第6期

机译：3D神经黑色素敏感的磁共振成像，半自动化的黑质致密部体积测量，用于诊断帕金森氏病
4. Segmentation of Substantia Nigra for the Automated Characterization of Parkinson’s Disease [C] . Dibash Basukala, Ramakrishnan Mukundan, Tracy Melzer, International Image Processing, Applications and Systems Conference . 2018

机译：黑质的分割，用于帕金森氏病的自动表征
5. A study of the dynamics of the protein core of the L99A mutant of T4 lysozyme using nuclear magnetic resonance relaxation dispersion. [D] . Hon, Bin. 2002

机译：T4溶菌酶L99A突变体的蛋白核动力学的核磁共振弛豫分散研究。
6. Increased iron-deposition in lateral-ventral substantia nigra pars compacta: A promising neuroimaging marker for Parkinsons disease [O] . Naying He, Jason Langley, Daniel E. Huddleston, 2020

机译：在腹侧腹侧腹膜内的铁沉积增加了NIGRA PARSCACTCA：帕金森病的一个有希望的神经影像标记
7. 3D neuromelanin-sensitive magnetic resonance imaging with semi-automated volume measurement of the substantia nigra pars compacta for diagnosis of Parkinson's disease [O] . Ogisu, Kimihiro, Kudo, Kohsuke, Sasaki, Makoto, 2013

机译：半自动黑质致密部的3D神经黑色素敏感磁共振成像和半自动体积测量，以诊断帕金森氏病

Nuclear magnetic relaxation dispersion profiles of substantia nigra pars compacta in Parkinson's disease patients are consistent with protein aggregation.

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