...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Neurochemistry International: The International Journal for the Rapid Publication of Critical Reviews, Preliminary and Original Research Communications in Neurochemistry >Neuronal nicotinic acetylcholine receptors: a new target site of ethanol.
【24h】

Neuronal nicotinic acetylcholine receptors: a new target site of ethanol.

机译：神经元烟碱型乙酰胆碱受体：乙醇的新靶位。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Whereas a variety of neuroreceptors and ion channels have been demonstrated to be affected by ethanol including GABAA receptors, NMDA receptors, non-NMDA glutamate receptors, 5-HT3 receptors and voltage-gated calcium channels, neuronal nicotinic acetylcholine receptors (nnAChRs) have recently emerged as a new target site of ethanol. The nnAChRs are different from the muscle type nicotinic AChRs with respect to their molecular architecture and pharmacology. This article briefly reviews the structure, distribution and function of nnAChRs for which a considerable amount of information has been rapidly accumulated during the past 5-10 years. The potent and unique action of ethanol on nnAChRs has been unveiled only during the past few years. Most recent developments along this line of ethanol action are discussed in this paper.
机译：尽管已证明乙醇可影响多种神经受体和离子通道，包括GABAA受体，NMDA受体，非NMDA谷氨酸受体，5-HT3受体和电压门控钙通道，但最近出现了神经元烟碱型乙酰胆碱受体（nnAChRs）。作为乙醇的新靶位。 nnAChR在分子结构和药理学方面不同于肌肉型烟碱型AChR。本文简要回顾了nnAChR的结构，分布和功能，在过去5到10年中已迅速积累了大量信息。乙醇对nnAChRs的有效而独特的作用仅在过去几年中才被揭露。本文讨论了乙醇作用这一方面的最新进展。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号