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首页> 外文期刊>Neuroradiology >Comparison of 64-row and 16-row multidetector CT in the perfusion CT evaluation of acute ischemic stroke patients receiving intravenous thrombolytic therapy
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Comparison of 64-row and 16-row multidetector CT in the perfusion CT evaluation of acute ischemic stroke patients receiving intravenous thrombolytic therapy

机译：急性缺血性脑卒中接受静脉溶栓治疗的灌注CT评估中64行和16行多探测器CT的比较

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Introduction Perfusion computed tomography (PCT) is increasingly performed in multimodal CT evaluation of acute ischemic stroke. We compared the technical quality of perfusion studies performed with a 16-row and a 64-row scanner and analyzed the differences between the scanners in their ability to detect perfusion defects. Methods We analyzed retrospectively the clinical and imaging data of 140 consecutive acute (<3 h) stroke patients who underwentmultimodal CTevaluation and received intravenous rtPA. Alberta Stroke Program Early CT Score (ASPECTS) was assigned to PCT maps. Clinical and imaging parameters were compared between the two scanners. Results There were more motion artifacts in the 16-row studies (p00.04), and the analysis software was able to completely correct significantly fewer of these (p<0.001). Both ASPECTS levels were optimally covered in only 29% of the 16-row studies, whereas in the 64-row studies, both levels were invariably optimally visualized (p<0.001). This significantly decreased the sensitivity of the 16-row scanner to detect perfusion defects in the upper ASPECTS level (p0 0.02). The 64-row scanner was able to detect more perfusion defects that were located entirely outside the ASPECTS regions (p00.03). There was no significant difference in the 3-month functional outcome. Conclusions The 16-row scanner suffered from limited anatomic coverage that decreased the sensitivity to detect perfusion defects in the cranial parts of the middle cerebral artery region. The 16-row studies had poorer technical quality that was in part attributable to higher sampling frequency and smaller slice thickness making the imaging more sensitive to small-scale movement of the patient.
机译：简介在急性缺血性卒中的多模式CT评估中，越来越多地使用灌注计算机断层扫描（PCT）。我们比较了使用16行和64行扫描仪进行的灌注研究的技术质量，并分析了扫描仪在检测灌注缺陷方面的差异。方法我们回顾性分析了140例接受多模式CT评估并接受rtPA静脉注射的连续性急性（<3 h）脑卒中患者的临床和影像学数据。艾伯塔省卒中计划的早期CT评分（ASPECTS）已分配给PCT地图。在两个扫描仪之间比较了临床和成像参数。结果16行研究中存在更多的运动伪影（p00.04），分析软件能够完全纠正这些伪影的数量更少（p <0.001）。在16行研究中，只有29％最优覆盖了这两种ASPECTS水平，而在64行研究中，这两种水平都始终是最优可视化的（p <0.001）。这大大降低了16行扫描仪检测ASPECTS较高水平（p0 0.02）的灌注缺陷的敏感性。 64行扫描仪能够检测更多完全位于ASPECTS区域之外的灌注缺陷（p00.03）。 3个月的功能结局无明显差异。结论16行扫描仪的解剖覆盖范围有限，降低了检测大脑中动脉区域颅骨部分灌注缺陷的敏感性。 16行研究的技术质量较差，部分原因是较高的采样频率和较小的切片厚度，使得成像对患者的小范围运动更加敏感。

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