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首页> 外文期刊>Neuron >GABAergic neurons: gate masters of the amygdala, mastered by dopamine.
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GABAergic neurons: gate masters of the amygdala, mastered by dopamine.

机译:GABA能神经元:杏仁核的门控,由多巴胺控制。

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摘要

A hyperdopaminergic state, such as stress, is associated with an increase in affective behavior. In this issue of Neuron, Marowsky and colleagues identify two clusters of paracapsular intercalated GABA neurons in amygdala slice preparations of GAD67-GFP mice. These GABA neurons mediate inhibition from cortical afferents to both the major input and output station of the amygdala, are inhibited during action of dopamine via D1 receptors, and are thus likely to represent important cellular players during dopaminergic disinhibition related to increased affective behavior.
机译:高多巴胺能状态,例如压力,与情感行为的增加有关。在本期《神经元》中,Marowsky及其同事在GAD67-GFP小鼠的杏仁体切片制剂中鉴定了两个簇状的荚膜内插GABA神经元簇。这些GABA神经元介导从皮质传入杏仁核的主要输入和输出站的抑制,在多巴胺通过D1受体作用期间被抑制,因此可能代表多巴胺能抑制作用中与重要的细胞行为有关,这与情感行为增加有关。

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