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首页> 外文期刊>Neuron >Strong single-fiber sensory inputs to olfactory cortex: implications for olfactory coding.
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Strong single-fiber sensory inputs to olfactory cortex: implications for olfactory coding.

机译:嗅觉皮质强大的单纤维感觉输入:嗅觉编码的含义。

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摘要

Olfactory information is first encoded in a combinatorial fashion by olfactory bulb glomeruli, which individually represent distinct chemical features of odors. This information is then transmitted to piriform (olfactory) cortex, via axons of olfactory bulb mitral and tufted (M/T) cells, where it is presumed to form the odor percept. However, mechanisms governing the integration of sensory information in mammalian olfactory cortex are unclear. Here we show that single M/T cells can make powerful connections with cortical pyramidal cells, and coincident input from few M/T cells is sufficient to elicit spike output. These findings suggest that odor coding is broad and distributed in olfactory cortex.
机译:嗅觉信息首先由嗅球小球以组合方式编码,它们分别代表气味的不同化学特征。然后,该信息通过嗅球二尖瓣和簇状(M / T)细胞的轴突传递至梨状(嗅觉)皮层,据推测在此处形成了气味感知。但是,尚不清楚控制哺乳动物嗅觉皮质中感觉信息整合的机制。在这里,我们显示单个M / T细胞可以与皮质锥体细胞建立强大的连接,而来自少数M / T细胞的重合输入足以引发尖峰输出。这些发现表明气味编码是广泛的并且分布在嗅觉皮质中。

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