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首页> 外文期刊>Neuropathology: official journal of the Japanese Society of Neuropathology >Craniopharyngiomas with a mixed histological pattern: the missing link to the intriguing pathogenesis of adamantinomatous and squamous-papillary varieties?
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Craniopharyngiomas with a mixed histological pattern: the missing link to the intriguing pathogenesis of adamantinomatous and squamous-papillary varieties?

机译：具有混合组织学模式的颅咽管瘤：缺少与金刚毛和鳞状乳头状变种有趣的发病机制的联系？

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摘要

CNS involvement by systemic Hodgkin lymphoma (HL) is quite rare, but the disease limited to the CNS is an exceptionally rare entity. The incidence of CNS-HL has been estimated at 0.2-0.5% of cases, but a more recent study has modified that figure to less than 0.02%. Like the conventional form, the diagnosis of primary CNS-HL rests upon distinct morphological and immunohistochemical characteristics, including diagnostic Reed-Sternberg cells, in addition to staging studies demonstrating a lack of disease elsewhere. The paucity of cases in the literature precludes reliable clinical and demographic data, as well as a consensus on treatment and prognosis. We present two cases of primary cerebellar HL, one with 10-year follow-up, and a relevant review of the literature.
机译：系统性霍奇金淋巴瘤（HL）参与CNS的情况非常少见，但仅限于CNS的疾病是极为罕见的个体。据估计，CNS-HL的发病率为0.2-0.5％，但最近的一项研究将该数字修改为小于0.02％。像常规形式一样，除了分阶段研究表明在其他地方没有疾病之外，对原发性CNS-HL的诊断还取决于独特的形态和免疫组织化学特征，包括诊断性Reed-Sternberg细胞。文献中病例少，因此无法获得可靠的临床和人口统计学数据，也无法就治疗和预后达成共识。我们介绍了两例原发性小脑HL，一例随访10年，并对文献进行了相关回顾。

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