Stem cell plasticity?

Frisen J

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Stem cell plasticity?

机译：干细胞可塑性？

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Cells differentiate according to stereotype pedigrees, or at least so we thought. Several studies have challenged this dogma and suggested that stem cells in several tissues may be plastic and switch lineages, but many of the results are open to other interpretations. Is there solid evidence for stem cell plasticity and should we rewrite the textbooks just yet?

机译：细胞根据定型谱系分化，或者至少我们如此认为。几项研究对这一教条提出了挑战，并提出几种组织中的干细胞可能是可塑性的，并且会转变谱系，但许多结果仍有待其他解释。是否有确凿的证据表明干细胞具有可塑性，我们是否应该重新编写教科书？

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《Neuron》 |2002年第3期|共4页
作者
Frisen J;
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正文语种 eng
中图分类神经生理学;
关键词
Cell Differentiation; Cell Lineage; Cell Nucleus; Embryo; Gene Expression Regulation; Developmental; 细胞分化; 细胞谱系; 细胞核; 胚胎; 基因表达调控; 发育期; 神经元可塑性; 干细胞;

机译：Cell Differentiation;Cell Lineage;Cell Nucleus;Embryo;Gene Expression Regulation;Developmental;细胞分化;细胞谱系;细胞核;胚胎;基因表达调控;发育期;神经元可塑性;干细胞;

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1. Characterization of stem cells and cancer cells on the basis of gene expression profile stability, plasticity, and robustness Dynamical systems theory of gene expressions under cell-cell interaction explains mutational robustness of differentiated cells and suggests how cancer cells emerge [J] . Kaneko Kunihiko . BioEssays : . 2011,第6期

机译：基于基因表达谱稳定性，可塑性和鲁棒性的干细胞和癌细胞表征在细胞-细胞相互作用下基因表达的动态系统理论解释了分化细胞的突变鲁棒性，并暗示了癌细胞如何出现
2. How hematopoietic stem cells know and act in cardiac microenvironment for stem cell plasticity? Impact of local renin-angiotensin systems. [J] . Ozturk MA, Guven GS, Haznedaroglu IC Medical hypotheses . 2004,第5期

机译：造血干细胞如何在心脏微环境中了解干细胞的可塑性并在其中发挥作用？局部肾素-血管紧张素系统的影响。
3. Precursor cells from Atlantic salmon (Salmo salar) visceral fat holds the plasticity to differentiate into the osteogenic lineage Precursor cells from Atlantic salmon (Salmo salar) visceral fat holds the plasticity to differentiate into the osteogenic lineage Precursor cells from Atlantic salmon (Salmo salar) visceral fat holds the plasticity to differentiate into the osteogenic lineage [J] . Elisabeth Ytteborg, Aleksei Krasnov, Harald Takle, Biology Open . 2015,第7期

机译：来自大西洋鲑鱼（Salmo salar）内脏脂肪的前体细胞具有可塑性，可分化为成骨谱系来自大西洋鲑鱼（Salmo salar）内脏脂肪的前体细胞具有可塑性，可分化为成骨谱系脂肪具有可塑性，可以分化为成骨细胞系
4. Interaction of Short-Term Neuronal Plasticity and Synaptic Plasticity Revealed by Nonlinear Systems Analysis in Dentate Granule Cells [C] . Xie, Xiaping, Song, Engineering in Medicine and Biology Society, 2006 Annual International Conference of the IEEE . 2006

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5. Epigenetic plasticity of cultured female human embryonic stem cells and regulation of gene expression and chromatin by PR-SET7 mediated H4K20me1. [D] . Veerappan, Chendhore Sai. 2012

机译：培养的女性人类胚胎干细胞的表观遗传可塑性以及PR-SET7介导的H4K20me1对基因表达和染色质的调节。
6. Auditory System Plasticity: Muscarinic acetylcholine receptors control baseline activity and Hebbian stimulus timing-dependent plasticity in fusiform cells of the dorsal cochlear nucleus [O] . Roxana A. Stefanescu, Susan E. Shore -1

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7. Intracellular Notch1 Signaling in Cancer-Associated Fibroblasts Dictates the Plasticity and Stemness of Melanoma Stem/Initiating Cells [O] . Yan Du, Hongwei Shao, Mecker Moller, 2019

机译：癌症相关成纤维细胞中的细胞内Notch1信号传导决定了黑色素瘤干/引发细胞的可塑性和茎

Stem cell plasticity?

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