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Age-related memory impairment. Is the cure worse than the disease?

机译:与年龄有关的记忆障碍。治愈胜于疾病吗?

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摘要

Aging impairs multiple memory systems. The neurochemical substrates of normal memory differ between memory systems. In this issue of Neuron, Ramos et al. find that activation of protein kinase A, which has been reported to improve hippocampal-dependent spatial memory in aged animals, has the opposite effect on prefrontal cortex-dependent working memory in aged animals.
机译:老化会损害多个内存系统。正常记忆的神经化学底物在记忆系统之间有所不同。在本期《神经元》中,拉莫斯等人。发现蛋白激酶A的激活据报道可改善老年动物的海马依赖性空间记忆,但对老年动物的前额叶皮层依赖性工作记忆具有相反的作用。

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